Osteoporosis, a metabolic bone disease characterized by low bone mineral density and
deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures …

The fracture risk assessment tool, FRAX®, was released in 2008 and provides country-
specific algorithms for estimating individualized 10-year probability of hip and major …

FRAX®, a simple-to-use fracture risk calculator, was first released in 2008 and since then
has been used increasingly worldwide. By calculating the 10-year probabilities of a major …

Osteoporosis care has evolved markedly over the last 50 years, such that there are now an
established clinical definition, validated methods of fracture risk assessment, and a range of …

The risk of a recurrent fragility fracture is particularly high immediately following the fracture.
This study provides adjustments to FRAX-based fracture probabilities accounting for the site …

Oral bisphosphonates are a key intervention in the treatment of osteoporosis and in
reducing the risk of fragility fractures. Their use is supported by over 3 decades of evidence; …

Purpose To provide updated evidence-based guidelines for the management of
osteoporosis in postmenopausal women in Belgium. Methods The Belgian Bone Club (BBC) …

Background Osteoporosis affects over half of adults over 50 years worldwide. With an
ageing population, osteoporosis, fractures and their associated costs are increasing …

To evaluate the reasons for inadequate adherence to osteoporosis therapy and to describe
the strategies for improving adherence to and persistence with regular medications, we …

Network meta-analysis compares multiple interventions and estimates the relative treatment
effects between all interventions, combining both direct and indirect evidence. Recently, a …