Caenorhabditis elegans lives in a complex habitat in which they routinely experience large
fluctuations in temperature, and encounter physical obstacles that vary in size and …

Biological materials such as extracellular matrix scaffolds, cancer cells, and tissues are often
assumed to respond elastically for simplicity; the viscoelastic response is quite commonly …

Focused ultrasound has been shown to stimulate excitable cells, but the biophysical
mechanisms behind this phenomenon remain poorly understood. To provide additional …

Chondrocyte mechanotransduction is not well understood, but recently, it has been
proposed that mechanically activated ion channels such as transient receptor potential …

Touch, hearing, and blood pressure regulation require mechanically gated ion channels that
convert mechanical stimuli into electrical currents. One such channel is Piezo1, which plays …

Several cell types experience repetitive mechanical stimuli, including vein endothelial cells
during pulsating blood flow, inner ear hair cells upon sound exposure, and skin cells and …

Piezo ion channels are sensors of mechanical forces and mediate a wide range of
physiological mechanotransduction processes. More than a decade of intense research has …

Unlike olfaction, taste, touch, vision, and proprioception, which are widespread across
animal phyla, hearing is found only in vertebrates and some arthropods. The vast majority of …

A growing body of work suggests that the material properties of biomolecular condensates
ensuing from liquid–liquid phase separation change with time. How this aging process is …

Molecular tension sensors have contributed to a growing understanding of mechanobiology.
However, the limited dynamic range and inability to specify the mechanical sensitivity of …