Pharmacogenetics of breast cancer treatments: a sub-Saharan Africa perspective

KC Nthontho, AK Ndlovu, K Sharma… - Pharmacogenomics …, 2022 - Taylor & Francis
Breast cancer is the most frequent cause of cancer death in low-and middle-income
countries, in particular among sub-Saharan African women, where response to available …

Health seeking behaviours and private sector delivery of care for non-communicable diseases in low-and middle-income countries: a systematic review

C Brindley, N Wijemunige, C Dieteren, J Bom… - BMC health services …, 2024 - Springer
Background Globally, non-communicable diseases (NCDs) are the leading cause of
mortality and morbidity placing a huge burden on individuals, families and health systems …

The pathogenic roles of lncRNA-Taurine upregulated 1 (TUG1) in colorectal cancer

S Azizidoost, A Nasrolahi, F Ghaedrahmati… - Cancer Cell …, 2022 - Springer
Colorectal cancer (CRC) is a gastrointestinal tumor that develops from the colon, rectum, or
appendix. The prognosis of CRC patients especially those with metastatic lesions remains …

Cost‐effectiveness of adjuvant chemotherapy for high‐risk stage II and stage III colon cancer in South Africa

SX Tan, Y Pumpalova, AM Rogers, K Bhatt… - Cancer …, 2023 - Wiley Online Library
Background Colon cancer incidence is rising in low‐and middle‐income countries (LMICs),
where resource limitations and cost often dictate treatment decisions. In this study, we …

UGT1A1 regulatory variant with potential effect on efficacy of HIV and cancer drugs commonly prescribed in South Africa

JM Mathew, PT Mpangase, D Sengupta… - …, 2021 - Taylor & Francis
Aim: Despite the high disease burden of human immunodeficiency virus (HIV) infection and
colorectal cancer (CRC) in South Africa (SA), treatment-relevant pharmacogenetic variants …

Cost Utility and Budget Impact Analysis of 5-fluorouracil and Capecitabine Based Regimens for Management of Colorectal Cancer at Kenyatta National Hospital

NJ Koech - 2022 - erepository.uonbi.ac.ke
Background Colorectal cancer (CRC) is the third most common cancer globally and it is the
fourth leading cause of cancer-related mortality. Management of CRC has progressively …

Pathology characteristics, prognostic determinants and the outcome of patients diagnosed with colorectal adenocarcinoma at University Teaching Hospital of Kigali

D Uwamariya - 2021 - dr.ur.ac.rw
Colorectal cancer (CRC) is the second most diagnosed cancer in female and the third in
men worldwide, arising from the epithelium of the colon and the rectum. It is known that …

[PDF][PDF] Identification of expression quantitative trait loci (EQTLS) and their functional impact on ADME genes

JM Mathew - 2021 - wiredspace.wits.ac.za
Polymorphisms in absorption, distribution, metabolism and excretion (ADME) genes result in
inter-individual variation in drug response, drug efficacy and adverse drug effects caused by …

Led Tabanlı Fotodinamik Tedavide Işık Dozu Etkisinin Kolorektal Kanser Hücreleri İçin İn Vitro Olarak Belirlenmesi

E Aksoy - 2021 - acikerisim.sakarya.edu.tr
Fotodinamik tedavi (FDT) halihazırda malign hastalıkların kontrolü için alternatif bir tedavi
olarak kullanılmaktadır. Fotosensitizer (FS) adı verilen ışığa duyarlı ajanın belirli bir dalga …