Rigidity versus flexibility: the dilemma of understanding protein thermal stability
A Karshikoff, L Nilsson, R Ladenstein - The FEBS journal, 2015 - Wiley Online Library
The role of fluctuations in protein thermostability has recently received considerable
attention. In the current literature a dualistic picture can be found: thermostability seems to …
attention. In the current literature a dualistic picture can be found: thermostability seems to …
The survival mechanisms of thermophiles at high temperatures: an angle of omics
Q Wang, Z Cen, J Zhao - Physiology, 2015 - journals.physiology.org
Thermophiles are referred to as microorganisms with optimal growth temperatures of> 60°
C. Over the past few years, a number of studies have been conducted regarding …
C. Over the past few years, a number of studies have been conducted regarding …
Understanding high-salt and cold adaptation of a polyextremophilic enzyme
The haloarchaeon Halorubrum lacusprofundi is among the few polyextremophilic organisms
capable of surviving in one of the most extreme aquatic environments on Earth, the Deep …
capable of surviving in one of the most extreme aquatic environments on Earth, the Deep …
Correlating enzyme annotations with a large set of microbial growth temperatures reveals metabolic adaptations to growth at diverse temperatures
MKM Engqvist - BMC microbiology, 2018 - Springer
Background The ambient temperature of all habitats is a key physical property that shapes
the biology of microbes inhabiting them. The optimal growth temperature (OGT) of a …
the biology of microbes inhabiting them. The optimal growth temperature (OGT) of a …
Crystal structure and molecular characterization of NADP+-farnesol dehydrogenase from cotton bollworm, Helicoverpa armigera
Farnesol dehydrogenase (FDL) orchestrates the oxidation reaction catalyzing farnesol to
farnesal, a key step in the juvenile hormone (JH) biosynthesis pathway of insects and hence …
farnesal, a key step in the juvenile hormone (JH) biosynthesis pathway of insects and hence …
Redesigning alcohol dehydrogenases/reductases for more efficient biosynthesis of enantiopure isomers
Alcohol dehydrogenases/reductases predominantly catalyze the asymmetric biosynthesis of
optically pure stereoisomers because of their unique chiral constitutions. The …
optically pure stereoisomers because of their unique chiral constitutions. The …
Microbe-aided thermophilic composting accelerates manure fermentation
L Wang, Y Li, X Li - Frontiers in microbiology, 2024 - frontiersin.org
Aerobic composting is a key strategy to the sustainable use of livestock manure, which is
however constrained by the slow kinetics. Microbe-aided thermophilic composting provides …
however constrained by the slow kinetics. Microbe-aided thermophilic composting provides …
Engineering diaryl alcohol dehydrogenase KpADH reveals importance of retaining hydration shell in organic solvent tolerance
L Zhang, W Dai, S Rong, U Schwaneberg… - Protein …, 2024 - Wiley Online Library
Alcohol dehydrogenases (ADHs) are synthetically important biocatalysts for the asymmetric
synthesis of chiral alcohols. The catalytic performance of ADHs in the presence of organic …
synthesis of chiral alcohols. The catalytic performance of ADHs in the presence of organic …
Quantitative proteomics reveals the temperature-dependent proteins encoded by a series of cluster genes in Thermoanaerobacter tengcongensis
Comprehensive and quantitative information of the thermophile proteome is an important
source for understanding of the survival mechanism under high growth temperature …
source for understanding of the survival mechanism under high growth temperature …
Rational design of Kluyveromyces marxianus ZJB14056 aldo–keto reductase KmAKR to enhance diastereoselectivity and activity
YJ Wang, BB Ying, W Shen, RC Zheng… - Enzyme and Microbial …, 2017 - Elsevier
Abstract t− Butyl 6− cyano−(3R, 5R)− dihydroxyhexanoate ((3R, 5R)− 1b) is a valuable chiral
synthon of atorvastatin calcium. A novel NADPH-specific aldo− keto reductase (AKR) was …
synthon of atorvastatin calcium. A novel NADPH-specific aldo− keto reductase (AKR) was …