After an acute ischemic stroke (AIS), inflammatory processes are able to concomitantly
induce both beneficial and detrimental effects. In this narrative review, we updated evidence …

Stroke is a leading cause of morbidity and mortality in western populations, with up to 40%
of survivors not expected to recover independence from severe disabilities. This equates to …

Objective: We investigated the association between circulating biomarkers of inflammation
and MRI markers of small vessel disease. Methods: We performed a cross-sectional study …

Osteoprotegerin (OPG) is a secreted glycoprotein central to bone turnover via its role as a
decoy receptor for the receptor activator of nuclear factor κB ligand (RANKL) and has …

Cerebral small vessel disease (CSVD) is a group of pathological processes affecting small
arteries, arterioles, capillaries, and small veins of the brain. It is one of the most common …

Several distinct lines of investigation in the context of atherosclerosis dealing with low-grade
inflammation, oxidative stress and platelet activation are now emerging, with CD40/CD40L …

The diagnosis of pulmonary arterial hypertension (PAH) is frequently delayed. We
hypothesized that circulating angiogenic modulatory protein levels might correspond with …

Objective There is plenty of evidence that osteoprotegerin (OPG) is linked to subclinical
vascular damage and predicts cardiovascular disease in high-risk populations. Our aim is to …

Small vessel disease (SVD) is a highly prevalent disorder of the brain's microvessels and a
common cause of dementia as well as ischaemic and haemorrhagic strokes. Though much …

Jensen JK, Ueland T, Atar D, Gullestad L, Mickley H, Aukrust P, Januzzi JL (Odense
University Hospital, Denmark; Rikshospitalet, Oslo, Norway; Massachusetts General …