Defining postpartum uterine disease and the mechanisms of infection and immunity in the female reproductive tract in cattle

IM Sheldon, J Cronin, L Goetze, G Donofrio… - Biology of …, 2009 - academic.oup.com
Uterine microbial disease affects half of all dairy cattle after parturition, causing infertility by
disrupting uterine and ovarian function. Infection with Escherichia coli, Arcanobacterium …

The prostanoid EP4 receptor and its signaling pathway

U Yokoyama, K Iwatsubo, M Umemura, T Fujita… - Pharmacological …, 2013 - ASPET
The EP4 prostanoid receptor is one of four receptor subtypes for prostaglandin E2. It
belongs to the family of G protein–coupled receptors. It was originally identified, similar to …

Prostaglandin E2 inhibits alveolar macrophage phagocytosis through an E-prostanoid 2 receptor-mediated increase in intracellular cyclic AMP

DM Aronoff, C Canetti… - The Journal of Immunology, 2004 - journals.aai.org
Prostaglandin E 2 is a potent lipid mediator of inflammation that effects changes in cell
functions through ligation of four distinct G protein-coupled receptors (E-prostanoid (EP) 1 …

Prostaglandin E2 receptor distribution and function in the gastrointestinal tract

I Dey, M Lejeune, K Chadee - British journal of pharmacology, 2006 - Wiley Online Library
Prostaglandin E2 (PGE2) is one of the most important biologically active prostanoids found
throughout the gastrointestinal tract. Despite the fact that PGE2 regulates many …

Prostaglandin biosynthesis, transport, and signaling in corpus luteum: a basis for autoregulation of luteal function

JA Arosh, SK Banu, P Chapdelaine, E Madore… - …, 2004 - academic.oup.com
The corpus luteum (CL) is a transient ovarian endocrine gland formed from the ovulated
follicle. Progesterone is the primary secretory product of CL and is essential for …

Transcriptomic analysis of the bovine endometrium: what is required to establish uterine receptivity to implantation in cattle?

N Forde, P Lonergan - Journal of Reproduction and Development, 2012 - jstage.jst.go.jp
In cattle, the majority of pregnancy loss can be attributed to early embryonic loss which
occurs prior maternal recognition of pregnancy on Day 16 (Day 0= ovulation). During this …

A genome‐wide scan for signatures of recent selection in Holstein cattle

S Qanbari, ECG Pimentel, J Tetens, G Thaller… - Animal …, 2010 - Wiley Online Library
The data from the newly available 50 K SNP chip was used for tagging the genome‐wide
footprints of positive selection in Holstein–Friesian cattle. For this purpose, we employed the …

Effect of interferon-τ on prostaglandin biosynthesis, transport, and signaling at the time of maternal recognition of pregnancy in cattle: evidence of polycrine actions of …

JA Arosh, SK Banu, S Kimmins, P Chapdelaine… - …, 2004 - academic.oup.com
Recognition and establishment of pregnancy involve several molecular and cellular
interactions among the conceptus, uterus, and corpus luteum (CL). In ruminants, interferon-τ …

Prostaglandins regulate conceptus elongation and mediate effects of interferon tau on the ovine uterine endometrium

P Dorniak, FW Bazer, TE Spencer - Biology of reproduction, 2011 - academic.oup.com
In ruminants, both the endometrium and the conceptus (embryo and associated
extraembryonic membranes) trophectoderm synthesizes and secretes prostaglandins (PG) …

[HTML][HTML] Conceptus-derived prostaglandins regulate gene expression in the endometrium prior to pregnancy recognition in ruminants

TE Spencer, N Forde, P Dorniak… - Reproduction …, 2013 - ncbi.nlm.nih.gov
In cattle, the blastocyst hatches from the zona pellucida on days 8 to 9 and then forms a
conceptus that grows and elongates into an ovoid and then filamentous shape between …