Breast cancer is the most commonly diagnosed cancer in women. Metastasis is the primary
cause of mortality for breast cancer patients. Multiple mechanisms underlie breast cancer …

Triple-negative breast cancer (TNBC) is a subtype of human breast cancer with one of the
worst prognoses, with no targeted therapeutic strategies currently available. Regulated cell …

Breast cancer is the most commonly diagnosed cancer and second-leading cause of cancer
deaths in women. Breast cancer stem cells (BCSCs) promote metastasis and therapeutic …

Introduction Breast cancer (BC) accounts for the majority of cancers among the female
population. Anomalous activation of various signaling pathways has become an issue of …

Simple Summary Many signaling pathways are overactive in breast cancer, and among
them is the STAT3 signaling pathway. STAT3 is activated by secreted factors within the …

Triple-negative breast cancer (TNBC) is associated with a poor prognosis and the absence
of targeted therapy. c-Kit, a receptor tyrosine kinase (RTK), is considered a molecular target …

Objective (s): Breast cancer is the most prevalent cancer among females with different
molecular subtypes. Corosolic acid is a pentacyclic triterpenoid with anti-cancer properties …

Introduction Signal transducer and activator of transcription 3 (STAT3) is involved in cancer
initiation and resistance to chemo-radiation therapies and targeted agents. The role of …

Cancer vaccine-based immunotherapy has great potential; however, the vaccines have
been hindered by the immunosuppressive tumor microenvironment (TME). In this study, dual …

Introduction Triple‐negative breast cancer (TNBC) patients have the poorest clinical
outcomes compared to other molecular subtypes of breast cancer. IL6/JAK/STAT3 signalling …