Excipients are generally pharmacologically inert, but can interact with drugs in the dosage
form and the physiological factors at the site of absorption to affect the bioavailability of a …

The aim was to improve the oral bioavailability and antihypertensive activity of poorly
soluble drug valsartan (VAL) by modifying the design and delivery of mesoporous silica …

Dissolution testing is a valuable tool that provides key information about bioavailability or
bioequivalency as well as batch to batch consistency of drug. Since the number of poorly …

The ability to predict in vivo response of an oral dosage form based on an in vitro technique
has been a sought after goal of the pharmaceutical scientist. Dissolution testing that …

The purpose of the study was to develop and internally validate a nonlinear in vitro–in vivo
correlation model for a chronotherapeutically programmed HPMC based propranolol HCl …

Excipients are generally pharmacologically inert, but can interact with drugs in the dosage
form and the physiological factors at the site of absorption to affect the bioavailability of a …

Oxidative deamination of the GABAA partial agonist CP-409,092 and sumatriptan represents
a major metabolic pathway and seems to play an important role for the clearance of these …

A controlled release formulation of captopril which was coated and fabricated into a donut
shaped tablet formulation, was investigated in rabbit for pharmacokinetic and in vitro–in vivo …

In vitro performance tests, such as dissolution tests, are performed for orally administered
non-solution dosage forms for a variety of reasons. It is one of the quality control tests for oral …

Self-emulsifying drug delivery systems (SEDDS) include self-microemulsifying drug delivery
system (SMEDDS) and self-nanoemulsifying drug delivery system (SNEDDS) whose major …