Abstract Interleukin-6 (IL-6) is a pleiotropic cytokine with significant functions in the
regulation of the immune system. As a potent pro-inflammatory cytokine, IL-6 plays a pivotal …

This review summarizes recent evidence concerning molecular changes in the commonest
type of lymphoma, diffuse large-B-cell lymphoma. Detailed studies have revealed three …

Profiling of circulating tumor DNA (ctDNA) in the bloodstream shows promise for
noninvasive cancer detection. Chromatin fragmentation features have previously been …

Gastric cancer (GC) is one of the leading causes of cancer-related deaths and shows high
levels of heterogeneity. The development of a specific prognostic model is important if we …

Abstract The International Prognostic Index (IPI) has been the basis for determining
prognosis in patients with aggressive non-Hodgkin lymphoma (NHL) for the past 20 years …

Monoclonal antibodies are standard therapeutics for several cancers including the anti-
CD20 antibody rituximab for B cell non-Hodgkin lymphoma (NHL). Rituximab and other …

Objective Despite several clinicopathological factors being integrated as prognostic
biomarkers, the individual variants and risk stratification have not been fully elucidated in …

Super-enhancers are an emerging subclass of regulatory regions controlling cell identity
and disease genes. However, their biological function and impact on miRNA networks are …

Because the causes of most lymphoid neoplasms remain unknown, comparison of
incidence patterns by disease subtype may provide critical clues for future etiologic …

Purpose Recent findings that human serum contains stably expressed microRNA (miRNA)
have revealed a great potential of serum miRNA signature as disease fingerprints to predict …