Human organs-on-chips for disease modelling, drug development and personalized medicine
DE Ingber - Nature Reviews Genetics, 2022 - nature.com
The failure of animal models to predict therapeutic responses in humans is a major problem
that also brings into question their use for basic research. Organ-on-a-chip (organ chip) …
that also brings into question their use for basic research. Organ-on-a-chip (organ chip) …
Microfluidic devices: a tool for nanoparticle synthesis and performance evaluation
The use of nanoparticles (NPs) in nanomedicine holds great promise for the treatment of
diseases for which conventional therapies present serious limitations. Additionally, NPs can …
diseases for which conventional therapies present serious limitations. Additionally, NPs can …
Nanoparticle-based delivery systems for vaccines
Vaccination is still the most cost-effective way to combat infectious illnesses. Conventional
vaccinations may have low immunogenicity and, in most situations, only provide partial …
vaccinations may have low immunogenicity and, in most situations, only provide partial …
Revolutionizing drug development: harnessing the potential of organ-on-chip technology for disease modeling and drug discovery
N Sunildutt, P Parihar… - Frontiers in …, 2023 - frontiersin.org
The inefficiency of existing animal models to precisely predict human pharmacological
effects is the root reason for drug development failure. Microphysiological system/organ-on …
effects is the root reason for drug development failure. Microphysiological system/organ-on …
Metal‐based nanomaterials and nanocomposites as promising frontier in cancer chemotherapy
S Kumar, MK Shukla, AK Sharma, GK Jayaprakash… - MedComm, 2023 - Wiley Online Library
Cancer is a disease associated with complex pathology and one of the most prevalent and
leading reasons for mortality in the world. Current chemotherapy has challenges with …
leading reasons for mortality in the world. Current chemotherapy has challenges with …
Biogenic synthesis of zinc oxide nanorods for biomedical applications and photodegradation of Rhodamine B
SO Aisida, C Onwujiobi, I Ahmad, T Zhao… - Materials Today …, 2022 - Elsevier
The biogenic synthesis protocol of functional oxides from the extract of plants for biomedical
applications has gained more attention recently. This work involves a biogenic synthesis of …
applications has gained more attention recently. This work involves a biogenic synthesis of …
Nanopriming Action of Microwave-Assisted Biofunctionalized ZnO Nanoparticles to Enhance the Growth under Moisture Stress in Vigna radiata
R Kalimuthu, K Meenachi Sellan, D Antony… - ACS …, 2023 - ACS Publications
Bare and stabilized zinc oxide nanoparticles (ZnO NPs) were prepared by a microwave-
assisted method and used as a priming agent to improve the morphological, physiological …
assisted method and used as a priming agent to improve the morphological, physiological …
Experimental methods for the biological evaluation of nanoparticle-based drug delivery risks
Many novel medical therapies use nanoparticle-based drug delivery systems, including
nanomaterials through drug delivery systems, diagnostics, or physiologically active …
nanomaterials through drug delivery systems, diagnostics, or physiologically active …
Sustainable fabrication of hybrid silver-copper nanocomposites (Ag‐CuO NCs) using Ocimum americanum L. as an effective regime against antibacterial, anticancer …
DB Manikandan, M Arumugam, A Sridhar… - Environmental …, 2023 - Elsevier
In this study, a sustainable fabrication of hybrid silver-copper oxide nanocomposites (Ag–
CuO NCs) was accomplished utilizing Ocimum americanum L. by one pot green chemistry …
CuO NCs) was accomplished utilizing Ocimum americanum L. by one pot green chemistry …
Organ-on-chip systems as a model for nanomedicine
Nanomedicine is giving rise to increasing numbers of successful drugs, including cancer
treatments, molecular imaging agents, and novel vaccine formulations. However …
treatments, molecular imaging agents, and novel vaccine formulations. However …