Hormones are potent endo-, para-, and autocrine endogenous regulators of the function of
multiple organs, including the heart. Endocrine dysfunction promotes a number of …

Steroid receptors (SRs) encompass a family of transcription factors that regulate the
expression of thousands of genes upon binding to steroid hormones and include the …

BACKGROUND: Ventricular arrhythmias (VAs) demonstrate a prominent day-night rhythm,
commonly presenting in the morning. Transcriptional rhythms in cardiac ion channels …

In mammals, the physiological activation of the glucocorticoid receptor (GR) by
glucocorticoids (GCs) promotes the maturation of cardiomyocytes during late gestation, but …

Sepsis is the major cause of mortality across intensive care units globally, yet details of
accompanying pathological molecular events remain unclear. This knowledge gap has …

Although the structural and functional effects of exercise on the heart are well established,
the metabolic changes that occur in the heart during and after exercise remain unclear. In …

Steroid receptors (SRs) are ligand-dependent transcription factors (TFs) relevant to key
cellular processes in both physiology and pathology, including some types of cancer. SOX2 …

Technological advancement, data democratisation, and decreasing costs have led to a
revolution in molecular biology in which the entire set of DNA, RNA, proteins, and various …

Glucocorticoids (GCs) exert potent antiproliferative and anti-inflammatory properties,
explaining their therapeutic efficacy for skin diseases. GCs act by binding to the GC receptor …

Glucocorticoids through activation of the Glucocorticoid receptor (GR) play an essential role
in cellular homeostasis during physiological variations and in response to stress. Our …