The ongoing quest for the first total artificial heart as destination therapy

A Vis, M Arfaee, H Khambati, MS Slaughter… - Nature Reviews …, 2022 - nature.com
Many patients with end-stage heart disease die because of the scarcity of donor hearts. A
total artificial heart (TAH), an implantable machine that replaces the heart, has so far been …

Mock circulatory loop applications for testing cardiovascular assist devices and in vitro studies

KW Xu, Q Gao, M Wan, K Zhang - Frontiers in Physiology, 2023 - frontiersin.org
The mock circulatory loop (MCL) is an in vitro experimental system that can provide
continuous pulsatile flows and simulate different physiological or pathological parameters of …

Interagency registry for mechanically assisted circulatory support report on the total artificial heart

FA Arabía, RS Cantor, DA Koehl, V Kasirajan… - The Journal of Heart and …, 2018 - Elsevier
Background We sought to better understand the patient population who receive a temporary
total artificial heart (TAH) as bridge to transplant or as bridge to decision by evaluating data …

A soft total artificial heart—first concept evaluation on a hybrid mock circulation

NH Cohrs, A Petrou, M Loepfe, M Yliruka… - Artificial …, 2017 - Wiley Online Library
The technology of 3D‐printing has allowed the production of entirely soft pumps with
complex chamber geometries. We used this technique to develop a completely soft …

A review of innovative electromagnetic technologies for a totally artificial heart

M Andriollo, E Fanton, A Tortella - Applied Sciences, 2023 - mdpi.com
A total artificial heart (TAH) represents a challenge in medical science to provide a survival
perspective for patients with severe cardiac problems. Although cardiac transplantation …

Fluid–structure interaction modelling of a positive-displacement Total Artificial Heart

J Bornoff, A Najar, L Fresiello, T Finocchiaro… - Scientific reports, 2023 - nature.com
For those suffering from end-stage biventricular heart failure, and where a heart
transplantation is not a viable option, a Total Artificial Heart (TAH) can be used as a bridge to …

A novel pumping principle for a total artificial heart

T Bierewirtz, K Narayanaswamy… - IEEE Transactions …, 2023 - ieeexplore.ieee.org
Objective: Total artificial hearts (TAH) serve as a temporary treatment for severe biventricular
heart failure. The limited durability and complication rates of current devices hamper long …

The heartmate 6

MA Daneshmand, M Bishawi, CA Milano… - ASAIO …, 2020 - journals.lww.com
The need for biventricular support poses significant challenges for patients who require a
mechanical bridge to transplantation. Recent improvements in ventricular assist device …

An algorithm for the computer aided design of coil couple for a misalignment tolerant biomedical inductive powering unit

AA Danilov, RR Aubakirov, EA Mindubaev… - IEEE …, 2019 - ieeexplore.ieee.org
Coils misalignments restrain the wider implementation of inductive powering of implantable
medical devices. The misalignment problem can be overcome with the help of the coils …

Toward portable artificial kidneys: the role of advanced microfluidics and membrane technologies in implantable systems

B Van Dang, RA Taylor, AJ Charlton… - IEEE Reviews in …, 2019 - ieeexplore.ieee.org
Globally, around 2.6 million people receive renal replacement therapy (RRT), and a further
4.9-9.7 million people need, but do not have access to, RRT [1]. The next generation RRT …