Epigenetic modifications in gastric cancer: Focus on DNA methylation

V Ebrahimi, A Soleimanian, T Ebrahimi, R Azargun… - Gene, 2020 - Elsevier
Gastric cancer is a complex heterogeneous disease which is the fourth prevalent
malignancy worldwide. Although, several diagnosis and treatment are available for the …

[HTML][HTML] Epigenetic role of thymoquinone: impact on cellular mechanism and cancer therapeutics

MA Khan, M Tania, J Fu - Drug discovery today, 2019 - Elsevier
Highlights•Thymoquinone is a natural product with anticancer activity.•Thymoquinone can
methylate or demethylate DNA.•Thymoquinone can interfere with the histone acetylation …

SNHG12 promotes angiogenesis following ischemic stroke via regulating miR-150/VEGF pathway

M Zhao, J Wang, X Xi, N Tan, L Zhang - Neuroscience, 2018 - Elsevier
The promotion of angiogenesis is a promising therapeutic strategy for ischemic stroke. Many
long noncoding RNAs (lncRNAs) are related to angiogenesis following ischemic stroke …

Zinc metalloproteins in epigenetics and their crosstalk

AP Yusuf, MB Abubakar, I Malami, KG Ibrahim… - Life, 2021 - mdpi.com
More than half a century ago, zinc was established as an essential micronutrient for normal
human physiology. In silico data suggest that about 10% of the human proteome potentially …

LncRNA MEG8 attenuates cerebral ischemia after ischemic stroke through targeting miR-130a-5p/VEGFA signaling

S Sui, L Sun, W Zhang, J Li, J Han, J Zheng… - Cellular and molecular …, 2021 - Springer
MEG8 is involved in ischemia stroke, however, its role in ischemia stroke remains unknown.
The current research aimed to investigate the effects and mechanisms of MEG8 in ischemic …

Noncoding RNA-mediated macrophage and cancer cell crosstalk in hepatocellular carcinoma

Z Zhou, Z Wang, J Gao, Z Lin, Y Wang, P Shan… - Molecular Therapy …, 2022 - cell.com
The tumor microenvironment (TME) is a well-recognized system that plays an essential role
in tumor initiation, development, and progression. Intense intercellular communication …

A review on epigenetic inheritance of experiences in humans

M Ghai, F Kader - Biochemical Genetics, 2022 - Springer
If genetics defines the inheritance of DNA, epigenetics aims to regulate and make it
adaptable. Epigenetic alterations include DNA methylation, chromatin remodelling, post …

The regulation of cyclins and cyclin-dependent kinases in the development of gastric cancer

A Javed, M Yarmohammadi, KS Korkmaz… - International Journal of …, 2023 - mdpi.com
Gastric cancer predominantly occurs in adenocarcinoma form and is characterized by
uncontrolled growth and metastases of gastric epithelial cells. The growth of gastric cells is …

Interaction of ncRNA and epigenetic modifications in gastric cancer: focus on histone modification

Q Yang, Y Chen, R Guo, Y Dai, L Tang, Y Zhao… - Frontiers in …, 2022 - frontiersin.org
Gastric cancer has developed as a very common gastrointestinal tumors, with recent
effective advancements in the diagnosis and treatment of early gastric cancer. However, the …

Long non-coding RNAs in hepatocellular carcinoma: ordering of the complicated lncRNA regulatory network and novel strategies for HCC clinical diagnosis and …

C Li, J Yang, C Liu, X Wang, L Zhang - Pharmacological research, 2020 - Elsevier
Although hepatocellular carcinoma (HCC) is a type of carcinoma with high malignancy, high
morbidity and low survival rate, its underlying mechanism has not been entirely elucidated …