[HTML][HTML] Do interleukin-1 and interleukin-6 antagonists hold any place in the treatment of atherosclerotic cardiovascular disease and related co-morbidities? an …

A Dimosiari, D Patoulias, GD Kitas… - Journal of Clinical …, 2023 - mdpi.com
Cardiovascular disease (CVD) constitutes a real pandemic of the 21st century. According to
data from the Centers for Disease Control and Prevention, one person dies every 34 min …

Signaling pathways in macrophages: molecular mechanisms and therapeutic targets

M Li, M Wang, Y Wen, H Zhang, GN Zhao, Q Gao - MedComm, 2023 - Wiley Online Library
Macrophages play diverse roles in development, homeostasis, and immunity. Accordingly,
the dysfunction of macrophages is involved in the occurrence and progression of various …

[HTML][HTML] Target and cell therapy for atherosclerosis and CVD

YV Markina, TV Kirichenko, TV Tolstik… - International Journal of …, 2023 - mdpi.com
Cardiovascular diseases (CVD) and, in particular, atherosclerosis, remain the main cause of
death in the world today. Unfortunately, in most cases, CVD therapy begins after the onset of …

[HTML][HTML] Deciphering the combination mechanisms of Gualou–Xiebai herb pair against atherosclerosis by network pharmacology and HPLC-Q-TOF-MS technology

Y Liu, H Zhong, P Xu, A Zhou, L Ding, J Qiu… - Frontiers in …, 2022 - frontiersin.org
Introduction: Gualou (Trichosanthes kirilowii Maxim)–Xiebai (Allium macrostemon
Bunge)(GLXB) is a well-known herb pair against atherosclerosis (AS). However, the …

[HTML][HTML] Lactobacillus gasseri RW2014 Ameliorates Hyperlipidemia by Modulating Bile Acid Metabolism and Gut Microbiota Composition in Rats

X Li, Y Xiao, Y Huang, L Song, M Li, Z Ren - Nutrients, 2022 - mdpi.com
Hyperlipidemia is a leading risk of cardiovascular and cerebrovascular disease. Dietary
supplementation with probiotics has been suggested as an alternative intervention to lower …

[HTML][HTML] Danlou tablet activates autophagy of vascular adventitial fibroblasts through PI3K/Akt/mTOR to protect cells from damage caused by atherosclerosis

L Wang, T Wu, C Si, H Wang, K Yue, S Shang… - Frontiers in …, 2021 - frontiersin.org
Danlou tablet (DLT), a commercial Chinese patent medicine, has been widely used to treat
cardiovascular diseases for many years. Atherosclerosis (AS) is the leading cause of …

[HTML][HTML] Identification of bioactive compounds and potential mechanisms of scutellariae radix-coptidis rhizoma in the treatment of atherosclerosis by integrating …

L Ji, T Song, C Ge, Q Wu, L Ma, X Chen, T Chen… - Biomedicine & …, 2023 - Elsevier
Objective This study aims at investigating the potential targets and functional mechanisms of
Scutellariae Radix-Coptidis Rhizoma (QLYD) against atherosclerosis (AS) through network …

[HTML][HTML] Targeting the crosstalk of immune response and vascular smooth muscle cells phenotype switch for arteriovenous fistula maturation

V Rai, H Singh, DK Agrawal - International Journal of Molecular Sciences, 2022 - mdpi.com
Plaque formation, thrombosis, and embolism are the underlying causes of acute
cardiovascular events such as myocardial infarction and stroke while early thrombosis and …

Association between coronary artery calcium and thoracic spine bone mineral density: Multiethnic Study of Atherosclerosis (MESA)

VS Manubolu, S Mao, A Kinninger, S Dahal… - Nutrition, Metabolism …, 2023 - Elsevier
Background and aims Previously, osteoporosis and coronary artery disease were
considered unrelated. However, beyond age, these two conditions appear to share common …

Oxidative stress-mediated programmed cell death: a potential therapy target for atherosclerosis

Y Chen, X Luo, B Xu, X Bao, H Jia, B Yu - Cardiovascular Drugs and …, 2022 - Springer
Nowadays, as a type of orderly and active death determined by genes, programmed cell
death (PCD), including apoptosis, pyroptosis, ferroptosis, and necroptosis, has attracted …