Kidney stones are mineral deposits in the renal calyces and pelvis that are found free or
attached to the renal papillae. They contain crystalline and organic components and are …

Kidney stone disease (nephrolithiasis) is a common problem that can be associated with
alterations in urinary solute composition including hypercalciuria. Studies suggest that the …

The European Association of Urology (EAU) Urolithiasis Guidelines Panel has prepared
these guidelines to help urologists assess evidence-based management of stones/calculi in …

Background and objective The aim of this review was to define patients who are at high risk
of recurrence of urolithiasis, to delineate diagnostic and therapeutic algorithms for each type …

Cystinuria, a genetic disorder of cystine transport, is characterized by excessive excretion of
cystine in the urine and recurrent cystine stones in the kidneys and, to a lesser extent, in the …

Cystinuria continues to be one of the most challenging stone diseases. During the latest
decades our knowledge of the molecular basis of cystinuria has expanded. Today 160 …

Amino acid transporters play very important roles in nutrient uptake, neurotransmitter
recycling, protein synthesis, gene expression, cell redox balance, cell signaling, and …

Background Cystinuria is a rare genetic kidney stone disease, with no cure. Current
treatments involve lowering urinary cystine levels and increasing cystine solubility. This …

Cystinuria is a genetic disease that leads to frequent formation of stones. In patients with
recurrent stone formation, particularly patients< 30 years old or those who have siblings with …

Cystinuria is an inherited disorder of the dibasic amino acid transport system in the proximal
tubule and the small intestine. Two responsible genes have been identified, the SLC3A1 on …