Supervised learning plays a key role in the operation of many biological and artificial neural
networks. Analysis of the computations underlying supervised learning is facilitated by the …

Most neurons in the mammalian CNS encode and transmit information via action potentials.
Knowledge of where these electrical events are initiated and how they propagate within …

Brief depolarization of cerebellar Purkinje cells was found to inhibit parallel fiber and
climbing fiber EPSCs for tens of seconds. This depolarization-induced suppression of …

Cerebellar Purkinje cells exhibit a unique type of synaptic plasticity, namely, long-term
depression (LTD). When two inputs to a Purkinje cell, one from a climbing fiber and the other …

Cerebellar long-term depression (LTD) is a calcium-dependent process in which coincident
activity of parallel fiber (PF) and climbing fiber (CF) synapses causes a long-lasting …

Behavioural learning is mediated by cellular plasticity, such as changes in the strength of
synapses at specific sites in neural circuits. The theory of cerebellar motor learning,, relies …

Canonically, each Purkinje cell (PC) in the adult cerebellum receives only one climbing fiber
(CF) from the inferior olive. Underlying current theories of cerebellar function is the notion …

Hippocampal inhibitory cells are diverse. It is supposed that they fall into functionally distinct
subsets defined by a similar morphology and physiology. Switching between functions could …

Exploring the organization and function of local inhibitory networks is an essential step on
the way to understand the principles of brain operation. We show here that molecular layer …

A key goal in functional neuroimaging is to use signals that are related to local changes in
metabolism and blood flow to track the neuronal correlates of mental activity. Recent …