Statistical estimation of a growth-fragmentation model observed on a genealogical tree

M Doumic, M Hoffmann, N Krell, L Robert - 2015 - projecteuclid.org
We raise the issue of estimating the division rate for a growing and dividing population
modelled by a piecewise deterministic Markov branching tree. Such models have broad …

The contribution of age structure to cell population responses to targeted therapeutics

P Gabriel, SP Garbett, V Quaranta, DR Tyson… - Journal of theoretical …, 2012 - Elsevier
Cells grown in culture act as a model system for analyzing the effects of anticancer
compounds, which may affect cell behavior in a cell cycle position-dependent manner. Cell …

Limit theorems for some branching measure-valued processes

B Cloez - Advances in Applied Probability, 2017 - cambridge.org
We consider a particle system in continuous time, a discrete population, with spatial motion,
and nonlocal branching. The offspring's positions and their number may depend on the …

Uniform sampling in a structured branching population

A Marguet - 2019 - projecteuclid.org
We are interested in the dynamic of a structured branching population where the trait of each
individual moves according to a Markov process. The rate of division of each individual is a …

An efficient kinetic model for assemblies of amyloid fibrils and its application to polyglutamine aggregation

S Prigent, A Ballesta, F Charles, N Lenuzza, P Gabriel… - PloS one, 2012 - journals.plos.org
Protein polymerization consists in the aggregation of single monomers into polymers that
may fragment. Fibrils assembly is a key process in amyloid diseases. Up to now, protein …

Analysis and simulation of division-and label-structured population models: a new tool to analyze proliferation assays

J Hasenauer, D Schittler, F Allgöwer - Bulletin of mathematical biology, 2012 - Springer
In most biological studies and processes, cell proliferation and population dynamics play an
essential role. Due to this ubiquity, a multitude of mathematical models has been developed …

Optimisation of cancer drug treatments using cell population dynamics

F Billy, J Clairambault, O Fercoq - Mathematical Methods and Models in …, 2012 - Springer
Cancer is primarily a disease of the physiological control on cell population proliferation.
Tissue proliferation relies on the cell division cycle: one cell becomes two after a sequence …

Self-similarity in a general aggregation–fragmentation problem. Application to fitness analysis

V Calvez, M Doumic, P Gabriel - Journal de mathématiques pures et …, 2012 - Elsevier
We consider the linear growth and fragmentation equation: with general coefficients τ, β and
κ. Under suitable conditions (see Doumic Jauffret and Gabriel, 2010 [1]), the first eigenvalue …

Estimating the division rate of the growth-fragmentation equation with a self-similar kernel

T Bourgeron, M Doumic, M Escobedo - Inverse Problems, 2014 - iopscience.iop.org
We consider the growth-fragmentation equation and we address the problem of estimating
the division rate from the stable size distribution of the population, which is easily measured …

Long-time asymptotics for nonlinear growth-fragmentation equations

P Gabriel - arXiv preprint arXiv:1102.2871, 2011 - arxiv.org
We are interested in the long-time asymptotic behavior of growth-fragmentation equations
with a nonlinear growth term. We present examples for which we can prove either the …