We review the recent biomedical detection developments of scanning near-field optical
microscopy (SNOM), focusing on scattering-type SNOM, atomic force microscope-based …

Small biomolecules at the subcellular level are building blocks for the manifestation of
complex biological activities. However, non-intrusive in situ investigation of biological …

Chemical imaging based on vibrational contrasts can extract molecular information
entangled in complex biological systems. To this end, nonlinear Raman scattering …

Scattering-type scanning near-field optical microscopy (s-SNOM) has emerged over the past
years as a powerful characterization tool that can probe important properties of advanced …

The ability to image cell chemistry at the nanoscale is key for understanding cell biology, but
many optical microscopies are restricted by the~(200–250) nm diffraction limit. Electron …

Vibrational spectroscopic techniques, both infrared absorption and Raman scattering, are
high precision, label free analytical techniques which have found applications in fields as …

We report the development and characterization of a detection technique for scattering-type
scanning near-field optical microscopy (s-SNOM) that enables near-field amplitude and …

The ability to track minute changes of a single amino acid residue in a cellular environment
is causing a paradigm shift in the attempt to fully understand the responses of biomolecules …

A thorough understanding of biological species and emerging nanomaterials requires,
among other efforts, their in-depth characterization through optical techniques capable of …

The design of soft biomaterials requires a deep understanding of molecular self‐assembly.
Here a nanoscale infrared (IR) spectroscopy study of a two‐component supramolecular gel …