The efficacy of nonsteroidal anti‐inflammatory drugs (NSAIDs) against inflammation, pain,
and fever has been supporting their worldwide use in the treatment of painful conditions and …

Bladder Cancer (BC) represents a clinical and social challenge due to its high incidence
and recurrence rates, as well as the limited advances in effective disease management …

Urothelial carcinoma is the most common form of bladder cancer, but pathway changes that
occur with stage‐wise progression have not been well defined. We used a metabolomics …

Background Trans-ferulic (FA) acid exhibits antioxidant effects in vitro. However, the
underlying mechanism of trans-FA activity in cellular physiology, especially cancer …

Despite advances in understanding of ovarian cancer biology, the progress in translation of
research findings into new therapies is still slow. It is associated in part with limitations of …

Abstract Cyclooxygenase-2 (COX-2), 5-Lipoxygenase (5-LOX), and epidermal growth factor
receptor (EGRF) are over-expressed in human pancreatic ductal adenocarcinoma (PDAC) …

Eicosanoids comprise a diverse group of bioactive lipids which orchestrate inflammation,
immunity, and tissue homeostasis, and whose dysregulation has been implicated in …

Background Non-steroidal anti-inflammatory drugs, cyclooxygenase (COX)-2 selective
inhibitors, have been explored for prevention and treatment of several inflammatory chronic …

Urothelial tumors, accompanied by mutations of the tumor suppressor protein TP53 and
dysregulation of mTOR signaling, are frequently associated with aggressive growth and …

Cancer chemopreventive agents inhibit the formation of precursor lesions and/or the
progression of these lesions to late stage disease. This approach to disease control has the …