Electroporation is being successfully used in biology, medicine, food processing, and
biotechnology, and in some environmental applications. Recent applications also include in …

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and catheter
ablation, which can be used in symptomatic patients refractory to antiarrhythmic therapy …

Electric pulses used in electroporation-based treatments have been shown to affect the
excitability of muscle and neuronal cells. However, understanding the interplay between …

Pulsed electric fields are increasingly used in medicine to transiently increase the cell
membrane permeability via electroporation to deliver therapeutic molecules into the cell …

Conventional electric stimuli of micro-and millisecond duration excite or activate cells at
voltages 10–100 times below the electroporation threshold. This ratio is remarkably different …

Targeted cellular ablation is being increasingly used in the treatment of arrhythmias and
structural heart disease. Catheter-based ablation for atrial fibrillation (AF) is considered a …

We compared membrane permeabilization by nanosecond pulsed electric field (nsPEF) in
HEK293 cells with and without assembled CaV1. 3 L-type voltage-gated calcium channel …

Background Myocardial tissue can be ablated by the application nanosecond pulsed fields
(nsPEFs). The applied electric fields irreversibly permeabilize cell membranes and thereby …

Electric field pulses of nano-and picosecond duration are a novel modality for
neurostimulation, activation of Ca 2+ signaling, and tissue ablation. However it is not known …

Background Ablation of cardiac tissue is an essential tool for the treatment of arrhythmias,
particularly of atrial fibrillation, atrial flutter, and ventricular tachycardia. Current ablation …