Cancer is a clonal disorder derived from a single ancestor cell and its progenies that are
positively selected by acquisition of 'driver mutations'. However, the evolution of positively …

Cancer is a group of cells that malignantly grow and proliferate uncontrollably. At present,
treatment modes for cancer mainly comprise surgery, chemotherapy, radiotherapy …

Clonal expansion in aged normal tissues has been implicated in the development of cancer.
However, the chronology and risk dependence of the expansion are poorly understood …

The Japan Gastroenterological Endoscopy Society has developed endoscopic submucosal
dissection/endoscopic mucosal resection guidelines. These guidelines present …

Background This is a consensus developed by a group of expert endoscopists aiming to
standardise the preparation, process and endoscopic procedural steps for diagnosis of early …

Acetaldehyde is a highly reactive compound that causes various forms of damage to DNA,
including DNA adducts, single-and/or double-strand breaks (DSBs), point mutations, sister …

METHODS: We performed endoscopic screening of 21,111 participants aged 40–69 years
from 3 high-risk areas of China in 2005–2009, and followed the cohort through 2016 …

Objectives The prognosis for pharyngeal cancer is relatively poor. It is usually diagnosed in
an advanced stage. Although the recent development of narrow‐band imaging (NBI) and …

Objective: To investigate the clinical and prognostic characteristics of patients with
esophageal cancer and multiple primary cancers. Summary Background Data: Patients with …

M2 macrophages contribute to the progression of oesophageal squamous cell carcinoma
(ESCC); however, the roles of M2 macrophages in early ESCC remain unclear. To clarify the …