The study of the structural changes and thermal stabilities of proteins in the presence of
various co-solutes is a critical element of basic research, drug discovery, and development …

One of the significant proteins that have attracted research groups due to virtue of being a
potent selective anticancer drug target and property of triggering apoptosis upon release in …

Heparin is one of the members of the glycosaminoglycan (GAG) family, which has been
associated with protein aggregation diseases including Alzheimer's disease, Parkinson's …

Even though there are a great number of possible conformational states, how a protein
generated as a linear unfolded polypeptide efficiently folds into its physiologically active …

It is known from in vitro studies that macromolecular crowding in the cell effects protein
structure, stability and function; but predictive studies are relatively unexplored. There are …

The intracellular environment is overcrowded with a range of molecules (small and large),
all of which influence protein conformation. As a result, understanding how proteins fold and …

We perform differential scanning calorimetry, broadband dielectric spectroscopy (BDS), and
nuclear magnetic resonance (NMR) studies to understand the molecular dynamics in …

The co-solute engineering is a rational approach to elucidate protein-molecule interactions
which involves an exhaustive understanding of the structural characteristics of active sites of …

Practically proteins perform their functions exposed to various molecules (macro/micro) of
different shapes, sizes, and high concentrations. In such conditions, proteins fold through …

Crowded environments, commonly found in the food system, are utilized to enhance the
properties of soybean proteins. Despite their widespread application, little information exists …