Missing data: A statistical framework for practice

JR Carpenter, M Smuk - Biometrical Journal, 2021 - Wiley Online Library
Missing data are ubiquitous in medical research, yet there is still uncertainty over when
restricting to the complete records is likely to be acceptable, when more complex methods …

Graphical models for processing missing data

K Mohan, J Pearl - Journal of the American Statistical Association, 2021 - Taylor & Francis
This article reviews recent advances in missing data research using graphical models to
represent multivariate dependencies. We first examine the limitations of traditional …

Ethnicity-specific BMI cutoffs for obesity based on type 2 diabetes risk in England: a population-based cohort study

R Caleyachetty, TM Barber, NI Mohammed… - The Lancet Diabetes & …, 2021 - thelancet.com
Background National and global recommendations for BMI cutoffs to trigger action to prevent
obesity-related complications like type 2 diabetes among non-White populations are …

[HTML][HTML] The proportion of missing data should not be used to guide decisions on multiple imputation

P Madley-Dowd, R Hughes, K Tilling, J Heron - Journal of clinical …, 2019 - Elsevier
Objectives Researchers are concerned whether multiple imputation (MI) or complete case
analysis should be used when a large proportion of data are missing. We aimed to provide …

Accounting for missing data in statistical analyses: multiple imputation is not always the answer

RA Hughes, J Heron, JAC Sterne… - International journal of …, 2019 - academic.oup.com
Background Missing data are unavoidable in epidemiological research, potentially leading
to bias and loss of precision. Multiple imputation (MI) is widely advocated as an …

[HTML][HTML] Exposure to air pollution is associated with an increased risk of metabolic dysfunction-associated fatty liver disease

B Guo, Y Guo, Q Nima, Y Feng, Z Wang, R Lu, Y Ma… - Journal of …, 2022 - Elsevier
Background & Aims Accumulating animal studies have demonstrated the harmful
contribution of ambient air pollution (AP) to metabolic dysfunction-associated fatty liver …

[HTML][HTML] Framework for the treatment and reporting of missing data in observational studies: the treatment and reporting of missing data in observational studies …

KJ Lee, KM Tilling, RP Cornish, RJA Little… - Journal of clinical …, 2021 - Elsevier
Missing data are ubiquitous in medical research. Although there is increasing guidance on
how to handle missing data, practice is changing slowly and misapprehensions abound …

Collider scope: when selection bias can substantially influence observed associations

MR Munafò, K Tilling, AE Taylor… - International journal …, 2018 - academic.oup.com
Large-scale cross-sectional and cohort studies have transformed our understanding of the
genetic and environmental determinants of health outcomes. However, the …

Principled approaches to missing data in epidemiologic studies

NJ Perkins, SR Cole, O Harel… - American journal of …, 2018 - academic.oup.com
Principled methods with which to appropriately analyze missing data have long existed;
however, broad implementation of these methods remains challenging. In this and 2 …

Finding genetically-supported drug targets for Parkinson's disease using Mendelian randomization of the druggable genome

CS Storm, DA Kia, MM Almramhi… - Nature …, 2021 - nature.com
Parkinson's disease is a neurodegenerative movement disorder that currently has no
disease-modifying treatment, partly owing to inefficiencies in drug target identification and …