Platelets are most important in providing cellular hemostasis but also take part in
inflammation and immune processes. Increased platelet size has been regarded as a …

Activated platelets play a role in the pathogenesis of coronary heart disease (CHD).
Following activation, platelets change shape, aggregate, and release several bioactive …

The relationship between MPV and platelet function was studied in human platelet
subpopulations separated on the basis of size by counterflow centrifugation. The original …

This study was undertaken to examine the interaction of platelet size and age in determining
in vitro platelet function. Baboon megakaryocytes were labeled in vivo by the injection of 75 …

The history and biologic significance of electronically measured mean platelet volumes is
discussed along with the issues and controversies surrounding both the aging of platelets in …

The relationship between platelet size and in vivo aging was investigated in the baboon
using size-dependent platelet subpopulations separated by counterflow centrifuga-tion. The …

New methods are described for platelet isolation and buoyant density determination using
low‐speed centrifugation in continuous density gradients of Percoll. The conditions used do …

We determined the platelet count and MPV in 100 normal subjects, in 147 subjects with
thrombocytopenia or thrombocytosis due to other than primary hematologic disorders, and in …

Background Platelets circulate in the blood of healthy individuals for approximately 7–10
days regulated by finely balanced processes of production and destruction. As platelets are …

To determine how alterations of megakaryocyte proliferation will affect platelet production,
we measured mean platelet volume (MPV), platelet volume heterogeneity, platelet count …