Cell–extracellular matrix mechanotransduction in 3D
A Saraswathibhatla, D Indana… - Nature Reviews Molecular …, 2023 - nature.com
Mechanical properties of extracellular matrices (ECMs) regulate essential cell behaviours,
including differentiation, migration and proliferation, through mechanotransduction. Studies …
including differentiation, migration and proliferation, through mechanotransduction. Studies …
Engineered hydrogels for mechanobiology
Cells' local mechanical environment can be as important in guiding cellular responses as
many well-characterized biochemical cues. Hydrogels that mimic the native extracellular …
many well-characterized biochemical cues. Hydrogels that mimic the native extracellular …
Volumetric bioprinting of organoids and optically tuned hydrogels to build liver‐like metabolic biofactories
PN Bernal, M Bouwmeester, J Madrid‐Wolff… - Advanced …, 2022 - Wiley Online Library
Organ‐and tissue‐level biological functions are intimately linked to microscale cell–cell
interactions and to the overarching tissue architecture. Together, biofabrication and …
interactions and to the overarching tissue architecture. Together, biofabrication and …
Engineered biomaterials for in situ tissue regeneration
In situ tissue regeneration harnesses the body's regenerative potential to control cell
functions for tissue repair. The design of biomaterials for in situ tissue engineering requires …
functions for tissue repair. The design of biomaterials for in situ tissue engineering requires …
The living interface between synthetic biology and biomaterial design
Recent far-reaching advances in synthetic biology have yielded exciting tools for the
creation of new materials. Conversely, advances in the fundamental understanding of soft …
creation of new materials. Conversely, advances in the fundamental understanding of soft …
Enhanced mechanosensing of cells in synthetic 3D matrix with controlled biophysical dynamics
Abstract 3D culture of cells in designer biomaterial matrices provides a biomimetic cellular
microenvironment and can yield critical insights into cellular behaviours not available from …
microenvironment and can yield critical insights into cellular behaviours not available from …
Mechanics of 3D cell–hydrogel interactions: experiments, models, and mechanisms
Hydrogels are highly water-swollen molecular networks that are ideal platforms to create
tissue mimetics owing to their vast and tunable properties. As such, hydrogels are promising …
tissue mimetics owing to their vast and tunable properties. As such, hydrogels are promising …
Local nascent protein deposition and remodelling guide mesenchymal stromal cell mechanosensing and fate in three-dimensional hydrogels
Hydrogels serve as valuable tools for studying cell–extracellular matrix interactions in three-
dimensional environments that recapitulate aspects of native extracellular matrix. However …
dimensional environments that recapitulate aspects of native extracellular matrix. However …
Robust hydrogel sensors for unsupervised learning enabled sign‐to‐verbal translation
Highly stretchable and robust strain sensors are rapidly emerging as promising candidates
for a diverse of wearable electronics. The main challenge for the practical application of …
for a diverse of wearable electronics. The main challenge for the practical application of …
The overview of porous, bioactive scaffolds as instructive biomaterials for tissue regeneration and their clinical translation
G Lutzweiler, A Ndreu Halili, N Engin Vrana - Pharmaceutics, 2020 - mdpi.com
Porous scaffolds have been employed for decades in the biomedical field where
researchers have been seeking to produce an environment which could approach one of …
researchers have been seeking to produce an environment which could approach one of …