Human-specific genetics: new tools to explore the molecular and cellular basis of human evolution

AA Pollen, U Kilik, CB Lowe, JG Camp - Nature Reviews Genetics, 2023 - nature.com
Our ancestors acquired morphological, cognitive and metabolic modifications that enabled
humans to colonize diverse habitats, develop extraordinary technologies and reshape the …

Museum genomics

DC Card, B Shapiro, G Giribet, C Moritz… - Annual Review of …, 2021 - annualreviews.org
Natural history collections are invaluable repositories of biological information that provide
an unrivaled record of Earth's biodiversity. Museum genomics—genomics research using …

The Allen Ancient DNA Resource (AADR) a curated compendium of ancient human genomes

S Mallick, A Micco, M Mah, H Ringbauer, I Lazaridis… - Scientific Data, 2024 - nature.com
More than two hundred papers have reported genome-wide data from ancient humans.
While the raw data for the vast majority are fully publicly available testifying to the …

Loss of extreme long-range enhancers in human neural crest drives a craniofacial disorder

HK Long, M Osterwalder, IC Welsh, K Hansen… - Cell Stem Cell, 2020 - cell.com
Non-coding mutations at the far end of a large gene desert surrounding the SOX9 gene
result in a human craniofacial disorder called Pierre Robin sequence (PRS). Leveraging a …

Current advances in primate genomics: novel approaches for understanding evolution and disease

D Juan, G Santpere, JL Kelley, OE Cornejo… - Nature reviews …, 2023 - nature.com
Primate genomics holds the key to understanding fundamental aspects of human evolution
and disease. However, genetic diversity and functional genomics data sets are currently …

More than a decade of genetic research on the Denisovans

S Peyrégne, V Slon, J Kelso - Nature Reviews Genetics, 2024 - nature.com
Denisovans, a group of now extinct humans who lived in Eastern Eurasia in the Middle and
Late Pleistocene, were first identified from DNA sequences just over a decade ago. Only ten …

The Persian plateau served as hub for Homo sapiens after the main out of Africa dispersal

L Vallini, C Zampieri, MJ Shoaee, E Bortolini… - Nature …, 2024 - nature.com
A combination of evidence, based on genetic, fossil and archaeological findings, indicates
that Homo sapiens spread out of Africa between~ 70-60 thousand years ago (kya) …

Twenty‐first century bioarchaeology: Taking stock and moving forward

JE Buikstra, SN DeWitte, SC Agarwal… - American journal of …, 2022 - Wiley Online Library
This article presents outcomes from a Workshop entitled “Bioarchaeology: Taking Stock and
Moving Forward,” which was held at Arizona State University (ASU) on March 6–8, 2020 …

Human–chimpanzee fused cells reveal cis-regulatory divergence underlying skeletal evolution

D Gokhman, RM Agoglia, M Kinnebrew, W Gordon… - Nature …, 2021 - nature.com
Gene regulatory divergence is thought to play a central role in determining human-specific
traits. However, our ability to link divergent regulation to divergent phenotypes is limited …

The cis-regulatory effects of modern human-specific variants

CV Weiss, L Harshman, F Inoue, HB Fraser, DA Petrov… - elife, 2021 - elifesciences.org
The Neanderthal and Denisovan genomes enabled the discovery of sequences that differ
between modern and archaic humans, the majority of which are noncoding. However, our …