Biological properties of extracellular vesicles and their physiological functions

M Yáñez-Mó, PRM Siljander, Z Andreu… - Journal of …, 2015 - Taylor & Francis
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …

Critical reevaluation of endothelial progenitor cell phenotypes for therapeutic and diagnostic use

GP Fadini, D Losordo, S Dimmeler - Circulation research, 2012 - Am Heart Assoc
Diverse subsets of endothelial progenitor cells (EPCs) are used for the treatment of ischemic
diseases in clinical trials, and circulating EPCs levels are considered as biomarkers for …

Applying extracellular vesicles based therapeutics in clinical trials–an ISEV position paper

T Lener, M Gimona, L Aigner, V Börger… - Journal of …, 2015 - Taylor & Francis
Extracellular vesicles (EVs), such as exosomes and microvesicles, are released by different
cell types and participate in physiological and pathophysiological processes. EVs mediate …

Assessing identity, phenotype, and fate of endothelial progenitor cells

KK Hirschi, DA Ingram, MC Yoder - … , thrombosis, and vascular …, 2008 - Am Heart Assoc
the Asahara at al10 article, human CD34 expressing cells (15.7% enriched for CD34
expression) in adult peripheral blood were interrogated as putative EPCs via in vitro and in …

Generation of induced pluripotent stem cells from human cord blood

A Haase, R Olmer, K Schwanke, S Wunderlich… - Cell stem cell, 2009 - cell.com
Induced pluripotent stem cells (iPSCs) may represent an ideal cell source for future
regenerative therapies. A critical issue concerning the clinical use of patient-specific iPSCs …

Endothelial progenitor cells: identity defined?

F Timmermans, J Plum, MC Yöder… - Journal of cellular …, 2009 - Wiley Online Library
• Introduction• The proof‐of‐concept in vivo: the cell, the read‐out and the animal model‐The
CEPC: Still a putative cell‐Do CEPCs play an essential role in vascular (patho) physiology …

CD34 positive cells as endothelial progenitor cells in biology and medicine

M Hassanpour, AA Salybekov, S Kobayashi… - Frontiers in cell and …, 2023 - frontiersin.org
CD34 is a cell surface antigen expressed in numerous stem/progenitor cells including
hematopoietic stem cells (HSCs) and endothelial progenitor cells (EPCs), which are known …

Circulating and tissue resident endothelial progenitor cells

DP Basile, MC Yoder - Journal of cellular physiology, 2014 - Wiley Online Library
Progenitor cells for the endothelial lineage have been widely investigated for more than a
decade, but continue to be controversial since no unique identifying marker has yet been …

Molecular analysis of endothelial progenitor cell (EPC) subtypes reveals two distinct cell populations with different identities

RJ Medina, CL O'Neill, M Sweeney… - BMC medical …, 2010 - Springer
Background The term endothelial progenitor cells (EPCs) is currently used to refer to cell
populations which are quite dissimilar in terms of biological properties. This study provides a …

Characterization of endothelial progenitor cell: past, present, and future

AA Salybekov, S Kobayashi, T Asahara - International journal of …, 2022 - mdpi.com
Endothelial progenitor cells (EPCs) are currently being studied as candidate cell sources for
revascularization strategies. Despite these promising results, widespread clinical …