Current research into the role of engineered nanoparticles in drug delivery systems (DDSs)
for medical purposes has developed numerous fascinating nanocarriers. This paper reviews …

The blood-brain barrier (BBB) is a dynamic structure that functions as a gatekeeper,
reflecting the unique requirements of the brain. In this review, following a brief historical …

The past decades have witnessed great progress in nanoparticle (NP)‐based brain‐
targeting drug delivery systems, while their therapeutic potentials are yet to be fully exploited …

The blood–brain barrier (BBB) is a highly regulated and efficient barrier that provides a
sanctuary to the brain. It is designed to regulate brain homeostasis and to permit selective …

Lipid nanoparticles based on solid matrix have emerged as potential drug carriers to
improve gastrointestinal (GI) absorption and oral bioavailability of several drugs, especially …

It has been established that oxidative stress, defined as the condition in which the sum of
free radicals in a cell exceeds the antioxidant capacity of the cell, contributes to the …

For the past few decades, there has been a considerable research interest in the area of
drug delivery using particulate delivery systems as carriers for small and large molecules …

Although many agents have therapeutic potentials for central nervous system (CNS)
diseases, few of these agents have been clinically used because of the brain barriers. As the …

Biodegradable nanoparticles (NPs) are gaining increased attention for their ability to serve
as a viable carrier for site specific delivery of vaccines, genes, drugs and other biomolecules …

Polymeric lipid hybrid nanoparticles (PLNs) are core–shell nanoparticles made up of a
polymeric kernel and lipid/lipid–PEG shells that have the physical stability and …