Inflammatory pathways in COVID‐19: mechanism and therapeutic interventions

Y Jiang, T Zhao, X Zhou, Y Xiang… - MedComm, 2022 - Wiley Online Library
Abstract The 2019 coronavirus disease (COVID‐19) pandemic has become a global crisis.
In the immunopathogenesis of COVID‐19, SARS‐CoV‐2 infection induces an excessive …

[HTML][HTML] COVID-19 disease and autoimmune disorders: A mutual pathway

M Al-Beltagi, NK Saeed, AS Bediwy - World Journal of …, 2022 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19) is a real challenge for humanity with high
morbidity and mortality. Despite being primarily a respiratory illness, COVID-19 can affect …

Anti-VEGF agents: As appealing targets in the setting of COVID-19 treatment in critically ill patients

A Sahebnasagh, SM Nabavi, HRK Kashani… - International …, 2021 - Elsevier
Recently, the medications used for the severe form of the coronavirus disease-19 (COVID-
19) therapy are of particular interest. In this sense, it has been supposed that anti-VEGF …

Analysis and identification of potential type II helper T cell (Th2)-Related key genes and therapeutic agents for COVID-19

Q Jin, W Li, W Yu, M Zeng, J Liu, P Xu - Computers in biology and medicine, 2022 - Elsevier
COVID-19 pandemic poses a severe threat to public health. However, so far, there are no
effective drugs for COVID-19. Transcriptomic changes and key genes related to Th2 cells in …

Bioinformatics and in-silico findings reveal medical features and pharmacological targets of biochanin A against colorectal cancer and COVID-19

J Qin, C Guo, L Yang, X Liang, A Jiao, KP Lai… - …, 2021 - Taylor & Francis
Severe mortality due to the COVID-19 pandemic resulted from the lack of effective treatment.
Although COVID-19 vaccines are available, their side effects have become a challenge for …

Regulation of tripartite motif-containing proteins on immune response and viral evasion

XZ Zhang, FH Li, XJ Wang - Frontiers in Microbiology, 2021 - frontiersin.org
Tripartite motif-containing proteins (TRIMs), exhibiting ubiquitin E3 ligase activity, are
involved in regulation of not only autophagy and apoptosis but also pyrotosis and antiviral …

[HTML][HTML] SARS-CoV-2, the angiotensin converting enzyme 2 (ACE2) receptor and Alzheimer's disease

WJ Lukiw - Journal of Alzheimer's disease & Parkinsonism, 2021 - ncbi.nlm.nih.gov
Coronavirus disease of the year 2019 (COVID-19) is categorized as an acute, rapid onset
viral pneumonia caused by the novel severe acute respiratory syndrome coronavirus 2 …

Adverse drug reactions associated with COVID-19 management

V Chavda, P Dodiya, V Apostolopoulos - … -Schmiedeberg's Archives of …, 2024 - Springer
The emergence of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
outbreak, which causes COVID-19, had a devastating impact on both people's lives and the …

Identification and evaluation of candidate COVID-19 critical genes and medicinal drugs related to plasma cells

Z Liu, OO Petinrin, N Chen, M Toseef, F Liu… - BMC Infectious …, 2024 - Springer
The ongoing COVID-19 pandemic, caused by the SARS-CoV-2 virus, represents one of the
most significant global health crises in recent history. Despite extensive research into the …

[PDF][PDF] Therapeutic Impact of Tocilizumab in the Setting of Severe COVID-19; an Updated and Comprehensive Review on Current Evidence

A Rezabakhsh, F Mojtahedi… - Archives of …, 2024 - journals.sbmu.ac.ir
Introduction: The COVID-19 pandemic caused by SARS-CoV-2 has been the major health
concern in 2019 globally. Considering the severity and phase of the disease, various …