Background Increasing rates of mental health problems among adolescents are of concern.
Teens who are most in need of mental health attention are reluctant to seek help. A better …

The alliance-outcome relationship has been consistently linked to positive treatment
outcomes irrespective of psychotherapy modality. However, beyond its general links to …

Clinical science seems to have reached a tipping point. It appears that a new paradigm is
beginning to emerge that is questioning the validity and utility of the medical illness model …

Group-based social skills interventions (GSSIs) are widely used for treating social
competence among youth with autism spectrum disorder (ASD), but their efficacy is unclear …

For decades the development of evidence-based therapy has been based on experimental
tests of protocols designed to impact psychiatric syndromes. As this paradigm weakens, a …

Depression in youth is prevalent and disabling and tends to presage a chronic and recurrent
course of illness and impairment in adulthood. Clinical trial research in youth depression …

This article provides a narrative review of studies that examined mechanisms of behavior
change in substance use disorder. Several mechanisms have some support, including self …

We present a vision of clinical science, based on a conceptual framework of intervention
development endorsed by the Delaware Project. This framework is grounded in an updated …

Evidence-based psychotherapies have been shown to be efficacious and cost-effective for a
wide range of psychiatric conditions. Psychiatric disorders are prevalent worldwide and …

Few clinical scientists would disagree that more research is needed on the underlying
mechanisms and processes of change in psychological therapies. In the dominant current …