[HTML][HTML] Hypoxia-induced H19/YB-1 cascade modulates cardiac remodeling after infarction
OK Choong, CY Chen, J Zhang, JH Lin, PJ Lin… - Theranostics, 2019 - ncbi.nlm.nih.gov
Rationale: Long non-coding RNA (lncRNAs) has been identified as a pivotal novel
regulators in cardiac development as well as cardiac pathogenesis. lncRNA H19 is known …
regulators in cardiac development as well as cardiac pathogenesis. lncRNA H19 is known …
Development and validation of Ran as a prognostic marker in stage I and stage II primary breast cancer
Purpose Existing prognostic biomarkers are inadequate for stratifying breast cancer patients
with the highest risk of tumor progression at the time of diagnosis. Here, we demonstrate that …
with the highest risk of tumor progression at the time of diagnosis. Here, we demonstrate that …
Yellow mealworm (Tenebrio Molitor) enhances intestinal immunity in largemouth bass (Micropterus salmoides) via the NFκB/survivin signaling pathway
C Ge, X Liang, X Wu, J Wang, H Wang, Y Qin… - Fish & Shellfish …, 2023 - Elsevier
This study aimed to elucidate the mechanisms of yellow mealworm (Tenebrio Molitor, YM) in
intestinal immunity and health. Largemouth bass, as an enteritis modeling animal, were fed …
intestinal immunity and health. Largemouth bass, as an enteritis modeling animal, were fed …
Simvastatin protects cardiomyocytes against endotoxin-induced apoptosis and up-regulates survivin/NF-κB/p65 expression
This study is aimed to investigate whether simvastatin induces cardiomyocytes survival
signaling in endotoxin (lipopolysaccharide, LSP)-induced myocardial injury, and if so, further …
signaling in endotoxin (lipopolysaccharide, LSP)-induced myocardial injury, and if so, further …
Amelioration of Endotoxin-Induced Acute Lung Injury and Alveolar Epithelial Cells Apoptosis by Simvastatin Is Associated with Up-Regulation of Survivin/NF-kB/p65 …
Disruption of the alveolar–endothelial barrier caused by inflammation leads to the
progression of septic acute lung injury (ALI). In the present study, we investigated the …
progression of septic acute lung injury (ALI). In the present study, we investigated the …
Protective effects of simvastatin on endotoxin-induced acute kidney injury through activation of tubular epithelial cells' survival and hindering cytochrome C-mediated …
Increasing evidence suggests that apoptosis of tubular cells and renal inflammation mainly
determine the outcome of sepsis-associated acute kidney injury (AKI). The study aim was to …
determine the outcome of sepsis-associated acute kidney injury (AKI). The study aim was to …
A nanobody-based molecular toolkit for ubiquitin–proteasome system explores the main role of survivin subcellular localization
H Miao, C Liu, H Ouyang, P Zhang, Y Liu… - … in Bioengineering and …, 2023 - frontiersin.org
Targeted protein degradation is a powerful tool for determining the function of specific
proteins nowadays. Survivin is the smallest member of the inhibitor of the apoptosis protein …
proteins nowadays. Survivin is the smallest member of the inhibitor of the apoptosis protein …
Overexpression of MRP1/ABCC1, Survivin and BCRP/ABCC2 Predicts the Resistance of Diffuse Large B-Cell Lymphoma to R-CHOP Treatment
Simple Summary This study aimed to investigate if the coexpression of ABC transporters
and survivin is associated with R-CHOP treatment response. Bcl-2 was in strong positive …
and survivin is associated with R-CHOP treatment response. Bcl-2 was in strong positive …
Ablation of survivin in T cells attenuates acute allograft rejection after murine heterotopic heart transplantation by inducing apoptosis
H Xu, J Yu, J Cui, Z Chen, X Zhang, Y Zou… - Frontiers in …, 2021 - frontiersin.org
Although studies in oncology have well explored the pharmacological effects of Birc5, little is
known about its role in allogeneic T-cell responses. Therefore, the present study used a …
known about its role in allogeneic T-cell responses. Therefore, the present study used a …
Identification of immune-related genes and small-molecule drugs in hypertension-induced left ventricular hypertrophy based on machine learning algorithms and …
M Zhou, T Li, S Lv, W Gan, F Zhang, Y Che… - Frontiers in …, 2024 - frontiersin.org
Background Left ventricular hypertrophy (LVH) is a common consequence of hypertension
and can lead to heart failure. The immune response plays an important role in hypertensive …
and can lead to heart failure. The immune response plays an important role in hypertensive …