Healthy lifestyle and diet are associated with significant reduction in risk of obesity, type 2
diabetes, and cardiovascular diseases. Oxidative stress and the imbalance between …

Atherosclerosis is a leading cause of morbidity and mortality in Western society. Despite
improved insight into disease pathogenesis and therapeutic options, additional treatment …

Introduction Intracellular reactive oxygen species (ROS) and nitric oxide (NO) levels are
associated with vascular homeostasis and diseases. Exercise can modulate ROS and NO …

Excessive angiogenesis (ie, the formation of new blood vessels) contributes to different
pathologies, among them cancer and ocular disorders. Conversely, dysfunction of …

Exercise exerts direct effects on the vasculature via the impact of hemodynamic forces on
the endothelium, thereby leading to functional and structural adaptations that lower …

Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease involving
airway closure and parenchyma destruction (emphysema). Cardiovascular diseases are the …

50% of patients with heart failure have a preserved ejection fraction (HFpEF). Numerous
studies have investigated the pathophysiological mechanisms of HFpEF and have shown …

We aimed to study the effects and underlying mechanism of different intensities of
continuous training (CT) on vascular inflammation and oxidative stress in spontaneously …

Melatonin, a neuroendocrine hormone synthesized primarily by the pineal gland, provides
various cardiovascular benefits. Regular physical activity is an effective non …

Generating precise in vivo arterial endothelial hemodynamic microenvironments using
microfluidics is essential for exploring endothelial mechanobiology. However, a …