The tumor microenvironment is proposed to contribute substantially to the progression of
cancers, including breast cancer. Cancer‐associated fibroblasts (CAFs) are the most …

Podoplanin is a small cell-surface mucin-like glycoprotein that plays a crucial role in the
development of the alveoli, heart, and lymphatic vascular system. Emerging evidence …

Cancer‐associated fibroblasts (CAF) are orchestrators of the pancreatic ductal
adenocarcinoma (PDAC) microenvironment. Stromal heterogeneity may explain differential …

Cardiac ischemia leads to the loss of myocardial tissue and the activation of a repair process
that culminates in the formation of a scar whose structural characteristics dictate propensity …

In cancer patients, immune cells are often functionally compromised due to the
immunosuppressive features of the tumor microenvironment (TME) which contribute to the …

Inflammation is known to play a critical role in all stages of tumorigenesis; however, less is
known about how it predisposes the tissue microenvironment preceding tumor formation …

At present, only a few reports have addressed the possible contribution of the lymphatic
vascular system to the pathogenesis of systemic sclerosis (SSc). Based on the evidence that …

Up till now, research on inflammatory bowel disease [IBD] has mainly been focused on the
immune cells present in the gastrointestinal tract. However, recent insights indicate that …

Background Cancer-associated thrombosis (CAT) is the leading cause of morbidity and
mortality. Cancer-associated fibroblasts (CAFs) are a prominent component of the tumor …

Breast cancer deaths are primarily caused by metastasis. There are several treatment
options that can be used to treat breast cancer. There are, however, a limited number of …