Synthetic glycans to improve current glycoconjugate vaccines and fight antimicrobial resistance
L Del Bino, KE Østerlid, DY Wu, F Nonne… - Chemical …, 2022 - ACS Publications
Antimicrobial resistance (AMR) is emerging as the next potential pandemic. Different
microorganisms, including the bacteria Acinetobacter baumannii, Clostridioides difficile …
microorganisms, including the bacteria Acinetobacter baumannii, Clostridioides difficile …
Mechanisms of antibiotic resistance in enterococci
Multidrug-resistant (MDR) enterococci are important nosocomial pathogens and a growing
clinical challenge. These organisms have developed resistance to virtually all antimicrobials …
clinical challenge. These organisms have developed resistance to virtually all antimicrobials …
The rise of the Enterococcus: beyond vancomycin resistance
CA Arias, BE Murray - Nature Reviews Microbiology, 2012 - nature.com
The genus Enterococcus includes some of the most important nosocomial multidrug-
resistant organisms, and these pathogens usually affect patients who are debilitated by …
resistant organisms, and these pathogens usually affect patients who are debilitated by …
Envelope structures of Gram-positive bacteria
M Rajagopal, S Walker - Protein and sugar export and assembly in Gram …, 2017 - Springer
Gram-positive organisms, including the pathogens Staphylococcus aureus, Streptococcus
pneumoniae, and Enterococcus faecalis, have dynamic cell envelopes that mediate …
pneumoniae, and Enterococcus faecalis, have dynamic cell envelopes that mediate …
Lipoteichoic acid synthesis and function in gram-positive bacteria
MG Percy, A Gründling - Annual review of microbiology, 2014 - annualreviews.org
Lipoteichoic acid (LTA) is an important cell wall polymer found in gram-positive bacteria.
Although the exact role of LTA is unknown, mutants display significant growth and …
Although the exact role of LTA is unknown, mutants display significant growth and …
Teichoic acids and related cell-wall glycopolymers in Gram-positive physiology and host interactions
C Weidenmaier, A Peschel - Nature Reviews Microbiology, 2008 - nature.com
Abstract Abstract| Most Gram-positive bacteria incorporate membrane-or peptidoglycan-
attached carbohydrate-based polymers into their cell envelopes. Such cell-wall …
attached carbohydrate-based polymers into their cell envelopes. Such cell-wall …
Potential targets for next generation antimicrobial glycoconjugate vaccines
F Micoli, P Costantino, R Adamo - FEMS microbiology reviews, 2018 - academic.oup.com
Cell surface carbohydrates have been proven optimal targets for vaccine development.
Conjugation of polysaccharides to a carrier protein triggers a T-cell-dependent immune …
Conjugation of polysaccharides to a carrier protein triggers a T-cell-dependent immune …
Comparative genomics of enterococci: variation in Enterococcus faecalis, clade structure in E. faecium, and defining characteristics of E. gallinarum and E …
The enterococci are Gram-positive lactic acid bacteria that inhabit the gastrointestinal tracts
of diverse hosts. However, Enterococcus faecium and E. faecalis have emerged as leading …
of diverse hosts. However, Enterococcus faecium and E. faecalis have emerged as leading …
[HTML][HTML] Pathogenesis and immunity in enterococcal infections
IG Sava, E Heikens, J Huebner - Clinical microbiology and infection, 2010 - Elsevier
Enterococcus faecalis and Enterococcus faecium have emerged as multi-resistant
nosocomial pathogens in immunocompromised and critically ill patients. Multi-resistant …
nosocomial pathogens in immunocompromised and critically ill patients. Multi-resistant …
Capsular Polysaccharide Production in Enterococcus faecalis and Contribution of CpsF to Capsule Serospecificity
Many bacterial species produce capsular polysaccharides that contribute to pathogenesis
through evasion of the host innate immune system. The gram-positive pathogen …
through evasion of the host innate immune system. The gram-positive pathogen …