In this review we will explore recent advances in the design and application of excited-state
intramolecular proton-transfer (ESIPT) based fluorescent probes. Fluorescence based …

Metabolic syndrome (MetS) is as a cluster of cardio-metabolic factors that greatly increase
the risk of chronic diseases such as type II diabetes mellitus and atherosclerotic …

Analyzing interstitial fluid (ISF) via microneedle (MN) devices enables patient health
monitoring in a minimally invasive manner and in point-of-care settings. However, most MN …

The perturbation in plasma free amino acid metabolome has been observed previously in
diabetes mellitus, and is associated with insulin resistance as well as the onset of …

Background & aims Metabolic syndrome (MetS) is associated with life-threatening
conditions. Several studies have reported an association of vitamin B12, folic acid, or …

Aim To evaluate circulating amino acids (AA) profiles in obesity, type 2 diabetes (T2D) and
metabolic syndrome (MetS). Methods Serum AA were profiled among 200; healthy, obese …

In obese children, hyperinsulinaemia induces adverse metabolic consequences related to
the risk of cardiovascular and other disorders. Branched‐chain amino acids (BCAA) and …

The onset and/or progression of type 2 diabetes (T2D) can be prevented if intervention is
early enough. As such, much effort has been placed on the search for indicators predictive of …

The secretion of insulin from pancreatic islet β-cells is critical for glucose homeostasis.
Disrupted insulin secretion underlies almost all forms of diabetes, including the most …

Oxidative stress plays a key role in the development of chronic diabetes-related
complications. Previous metabolomic studies showed a positive association of diabetes and …