Teleost fish possess an adaptive immune system associated with each of their mucosal
body surfaces. Evidence obtained from mucosal vaccination and mucosal infection studies …

The innate immune system is the only defence weapon of invertebrates and a fundamental
defence mechanism of fish. The innate system also plays an instructive role in the acquired …

Fifty years after the discovery of the mouse Mx1 gene, researchers are still trying to
understand the molecular details of the antiviral mechanisms mediated by Mx proteins. Mx …

The decline in the fisheries of traditional marine species has been an incentive for the
diversification of today's aquaculture sector into the intensive rearing of many finfish species …

Over the last three decades, the causative agent of viral encephalopathy and retinopathy
(VER) disease has become a serious problem of marine finfish aquaculture, and more …

This review summarizes the scattered literature on the effects of toxicants on the external
and internal innate immunity of fish. Insecticides, heavy metals and surfactants have been …

Recent results indicate that coherent models of how multiple interferons (IFN) are
recognized and signal selectively through a common receptor are now feasible. A proposal …

Mx proteins belong to the dynamin superfamily of high molecular weight GTPases and
interfere with multiplication of a wide variety of viruses. Earlier studies show that nuclear …

Infectious haematopoietic necrosis virus (IHNV) is a well-studied virus of salmonid fishes. A
highly efficacious DNA vaccine has been developed against this virus and studies have …

The aquaculture industry needs to augment its global production and efficiency to meet the
increasing consumer needs for fish and shellfish products. Unfortunately, infectious …