Introduction Infertility is defined as the inability to conceive after unprotected sexual
intercourse for at least 12 consecutive months. Our objective is to present an updated …

The type 1 parathyroid hormone receptor (PTHR1) binds, with equal affinity, two ligands with
distinct biological functions: PTH, the major peptide hormone controlling calcium …

Gonadotropin signaling classically involves proliferative, steroidogenic and apoptotic stimuli.
In this study, we used the human granulosa cell line hGL5 to demonstrate how follicle …

Context: Inactivating FSH receptor (FSHR) mutations can affect ovarian function, resulting in
variable clinical presentations ranging from primary amenorrhea to premature menopause …

Follicle‐stimulating hormone receptor (FSHR) is a class AG protein‐coupled receptor that
belongs to the subfamily of glycoprotein hormone receptors (GPHRs). The interaction of FSH …

Follicle-stimulating hormone (FSH) is produced in the pituitary and is essential for
reproduction. It specifically binds to a membrane receptor (FSHR) expressed in somatic cells …

When mutation is inactivated in the follicle-stimulating hormone receptor (FSHR) gene of
patients with amenorrhea, the receptor's functionality is abolished by completely blocking it …

В монографии рассмотрены структурно-функциональная организация гонадотропинов–
фолликулостимулирующего и лютеинизирующего гормонов и различных изоформ …

Purpose The thyroid-stimulating hormone receptor (TSHR) is the target autoantigen for
TSHR-stimulating autoantibodies in Graves' disease. The TSHR is composed of: a leucine …

Mutations in G protein-coupled receptors (GPCRs) underlie numerous diseases. Many
cause receptor misfolding and failure to reach the cell surface. Pharmacological chaperones …