The neurobiological basis of sex differences in learned fear and its inhibition
HLL Day, CW Stevenson - European Journal of Neuroscience, 2020 - Wiley Online Library
Learning that certain cues or environments predict threat enhances survival by promoting
appropriate fear and the resulting defensive responses. Adapting to changing stimulus …
appropriate fear and the resulting defensive responses. Adapting to changing stimulus …
Endozepines and their receptors: structure, functions and pathophysiological significance
MC Tonon, H Vaudry, J Chuquet, F Guillebaud… - Pharmacology & …, 2020 - Elsevier
The existence of specific binding sites for benzodiazepines (BZs) in the brain has prompted
the search for endogenous BZ receptor ligands designated by the generic term …
the search for endogenous BZ receptor ligands designated by the generic term …
Tumor suppressor p53 modulates activity-dependent synapse strengthening, autism-like behavior and hippocampus-dependent learning
Synaptic potentiation underlies various forms of behavior and depends on modulation by
multiple activity-dependent transcription factors to coordinate the expression of genes …
multiple activity-dependent transcription factors to coordinate the expression of genes …
Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite
Y Li, M Huang, M Wang, Y Wang, P Deng, C Li… - Cancer Cell, 2024 - cell.com
Tumors employ various strategies to evade immune surveillance. Central nervous system
(CNS) has multiple features to restrain immune response. Whether tumors and CNS share …
(CNS) has multiple features to restrain immune response. Whether tumors and CNS share …
The gliotransmitter ACBP controls feeding and energy homeostasis via the melanocortin system
K Bouyakdan, H Martin, F Liénard… - The Journal of …, 2019 - Am Soc Clin Investig
Glial cells have emerged as key players in the central control of energy balance and etiology
of obesity. Astrocytes play a central role in neural communication via the release of …
of obesity. Astrocytes play a central role in neural communication via the release of …
[HTML][HTML] The diversity of ACBD proteins–From lipid binding to protein modulators and organelle tethers
M Islinger, JL Costello, S Kors, E Soupene… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Members of the large multigene family of acyl-CoA binding domain containing proteins
(ACBDs) share a conserved motif required for binding of Coenzyme A esterified fatty acids of …
(ACBDs) share a conserved motif required for binding of Coenzyme A esterified fatty acids of …
From benzodiazepines to fatty acids and beyond: revisiting the role of ACBP/DBI
Four decades ago Costa and colleagues identified a small, secreted polypeptide in the brain
that can displace the benzodiazepine diazepam from the GABA A receptor, and was thus …
that can displace the benzodiazepine diazepam from the GABA A receptor, and was thus …
Refinement of the Barnes and Morris water maze protocols improves characterization of spatial cognitive deficits in the lithium-pilocarpine rat model of epilepsy
AV Dyomina, IV Smolensky, AV Zaitsev - Epilepsy & Behavior, 2023 - Elsevier
Temporal lobe epilepsy (TLE) often causes cognitive impairment, especially a decline in
spatial memory. Reductions in spatial memory and learning are also common in rodent …
spatial memory. Reductions in spatial memory and learning are also common in rodent …
[HTML][HTML] Evaluating the Clinical Significance of Diazepam Binding Inhibitor in Alzheimer's Disease: A Comparison with Inflammatory, Oxidative, and …
Introduction: Alzheimer's disease (AD) is one of the pathologies that the scientific world is
still desperate for. The aim of this study was the investigation of diazepam binding inhibitor …
still desperate for. The aim of this study was the investigation of diazepam binding inhibitor …
[Retracted] Molecular Basis of GABA Hypofunction in Adolescent Schizophrenia‐Like Animals
X Wang, Y Hu, W Liu, Y Ma, X Chen, T Xue… - Neural …, 2021 - Wiley Online Library
Schizophrenia is a neurodevelopmental disorder that NMDA receptor (NMDAR)
hypofunction appears centrally involved. Schizophrenia typically emerges in adolescence or …
hypofunction appears centrally involved. Schizophrenia typically emerges in adolescence or …