D614G mutation and SARS-CoV-2: impact on S-protein structure, function, infectivity, and immunity

M Bhattacharya, S Chatterjee, AR Sharma… - Applied microbiology …, 2021 - Springer
The progression of the COVID-19 pandemic has generated numerous emerging variants of
SARS-CoV-2 on a global scale. These variants have gained evolutionary advantages …

Impact of mutations in SARS-COV-2 spike on viral infectivity and antigenicity

W Zhou, C Xu, P Wang, AA Anashkina… - Briefings in …, 2022 - academic.oup.com
Since the outbreak of SARS-CoV-2, the etiologic agent of the COVID-19 pandemic, the viral
genome has acquired numerous mutations with the potential to alter the viral infectivity and …

[HTML][HTML] N‐terminal domain of SARS CoV‐2 spike protein mutation associated reduction in effectivity of neutralizing antibody with vaccinated individuals

Y Singh, NK Fuloria, S Fuloria… - Journal of Medical …, 2021 - ncbi.nlm.nih.gov
Dear Editor The spike (S) protein is a homotrimer on the SARS‐CoV‐2 surface which targets
the angiotensin‐converting enzyme‐2 in humans (ACE2). The Spike (S) coronavirus 2 …

Dynamics of viral infection and evolution of SARS-CoV-2 variants in the Calabria area of southern Italy

C De Marco, C Veneziano, A Massacci… - Frontiers in …, 2022 - frontiersin.org
In this study, we report on the results of SARS-CoV-2 surveillance performed in an area of
Southern Italy for 12 months (from March 2021 to February 2022). To this study, we have …

Novel coronavirus mutations: Vaccine development and challenges

WR Luo, XM Wu, W Wang, JL Yu, QQ Chen… - Microbial …, 2022 - Elsevier
The ongoing global pandemic of novel coronavirus pneumonia (COVID-19) caused by the
SARS-CoV-2 has a significant impact on global health and economy system. In this context …

SARS‐CoV‐2 spike glycoprotein‐reactive T cells can be readily expanded from COVID‐19 vaccinated donors

P Taborska, J Lastovicka, D Stakheev… - Immunity …, 2021 - Wiley Online Library
Introduction The COVID‐19 vaccine was designed to provide protection against infection by
the severe respiratory coronavirus 2 (SARS‐CoV‐2) and coronavirus disease 2019 (COVID …

The influence of single-point mutation D614G on the binding process between human angiotensin-converting enzyme 2 and the SARS-CoV-2 spike protein-an …

C Shi, Y Jiao, C Yang, Y Sun - RSC advances, 2023 - pubs.rsc.org
SARS-CoV-2 has continuously evolved as changes in the genetic code occur during
replication of the genome, with some of the mutations leading to higher transmission among …

Targeting COVID-19 Based on Pathogenesis

ZZ Chong, H Zhang - Authorea Preprints, 2024 - advance.sagepub.com
The new coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) are causing health crisis of the world. To control the …

БЕЛКИ SARS CoV-2 И БЕЛКИ ЧЕЛОВЕЧЕСКОГО ОРГАНИЗМА

АТ Марьянович, ДЮ Кормилец - Russian Biomedical Research …, 2024 - ojs3.gpmu.org
Аннотация Белки SARS CoV-2 представляют собой молекулы с массой от нескольких
десятков до нескольких тысяч аминокислотных остатков. Существуют структурные и …

Network analysis outlines strengths and weaknesses of emerging SARS-CoV-2 Spike variants

PD Manrique, S Chakraborty, K Nguyen, R Mansbach… - bioRxiv, 2021 - biorxiv.org
The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has triggered myriad efforts to
dissect and understand the structure and dynamics of this complex pathogen. The Spike …