Lung cancer is the leading cause of cancer deaths worldwide. Most of lung cancer cases are
classified as non-small cell lung cancers (NSCLC). EGFR has become an important …

Lung cancer is currently one of the most serious health issues in developed and developing
countries. There are multiple available treatment options; however survival still remains very …

Pyroptosis is a form of caspase-1-dependent programmed cell death with anti-tumor
properties, but the underlying molecular mechanisms are not fully understood. The results of …

Statins, known as HMG-CoA reductase (HMGCR) inhibitors, have primarily been utilized for
metabolic and angiographic medical applications because of their cholesterol-lowering …

Cancer is incurable because progressive phenotypic and genotypic changes in cancer cells
lead to resistance and recurrence. This indicates the need for the development of new drugs …

Aims Ehrlich ascites carcinoma and its subcutaneous inoculated solid tumour form (SEC)
are reliable models for chemotherapeutic molecular targets exploration. Novel …

Lung cancer is one of the most common causes of cancer-related mortality in the 21 st
century. Statins as inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase not only …

Lung cancer is a common neoplasm, usually treated through chemotherapy, radiotherapy
and/or surgery. Both clinical and experimental studies on cancer cells suggest that some …

Acquired radioresistance compromises the efficacy of radiotherapy for carcinomas including
esophageal cancer (EC), thus resulting in recurrence and poor survival. Recent research …

Solid tumor growth triggers a dynamic host response, which recapitulates wound healing
and defines the tumor microenvironment (TME). In addition to the action of the tumor cells …