[HTML][HTML] Helicobacter pylori infection: An overview of bacterial virulence factors and pathogenesis

CY Kao, BS Sheu, JJ Wu - Biomedical journal, 2016 - Elsevier
Helicobacter pylori pathogenesis and disease outcomes are mediated by a complex
interplay between bacterial virulence factors, host, and environmental factors. After H. pylori …

Helicobacter pylori and Gastric Cancer: Factors That Modulate Disease Risk

LE Wroblewski, RM Peek Jr… - Clinical microbiology …, 2010 - Am Soc Microbiol
Helicobacter pylori is a gastric pathogen that colonizes approximately 50% of the world's
population. Infection with H. pylori causes chronic inflammation and significantly increases …

[HTML][HTML] Role of Flagella in the Pathogenesis of Helicobacter pylori

H Gu - Current microbiology, 2017 - Springer
This review aimed to investigate the role of Helicobacter pylori flagella on the pathogenicity
of this bacterium in humans. Helicobacter pylori is a flagellated pathogen that colonizes the …

The role of motility as a virulence factor in bacteria

C Josenhans, S Suerbaum - International Journal of Medical Microbiology, 2002 - Elsevier
Many bacteria that cause diseases of humans, animals and plants use flagella to move. This
review summarises recent studies that have analysed the role of motility and chemotaxis in …

Helicobacter pylori Virulence and Genetic Geography

A Covacci, JL Telford, GD Giudice, J Parsonnet… - Science, 1999 - science.org
Isolated for the first time in 1982 from human gastric biopsy, Helicobacter pylori is
responsible for gastritis, peptic ulcer, and gastric cancer. A pathogenicity island acquired by …

Evasion of Toll-like receptor 5 by flagellated bacteria

E Andersen-Nissen, KD Smith… - Proceedings of the …, 2005 - National Acad Sciences
Toll-like receptor 5 (TLR5) recognizes an evolutionarily conserved site on bacterial flagellin
that is required for flagellar filament assembly and motility. The α and ε Proteobacteria …

[HTML][HTML] Pathogenesis and clinical management of Helicobacter pylori gastric infection

BB de Brito, FAF da Silva, AS Soares… - World journal of …, 2019 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) is a gram-negative bacterium that infects approximately 4.4
billion individuals worldwide. However, its prevalence varies among different geographic …

[HTML][HTML] Within-host evolution of Helicobacter pylori shaped by niche-specific adaptation, intragastric migrations and selective sweeps

F Ailloud, X Didelot, S Woltemate, G Pfaffinger… - Nature …, 2019 - nature.com
The human pathogen Helicobacter pylori displays extensive genetic diversity. While H.
pylori is known to evolve during infection, population dynamics inside the gastric …

Regulation cascade of flagellar expression in Gram-negative bacteria

OA Soutourina, PN Bertin - FEMS microbiology reviews, 2003 - academic.oup.com
Flagellar motility helps bacteria to reach the most favourable environments and to
successfully compete with other micro-organisms. These complex organelles also play an …

[HTML][HTML] Toll-like receptor (TLR) 2 and TLR5, but not TLR4, are required for Helicobacter pylori-induced NF-κB activation and chemokine expression by epithelial cells

MF Smith, A Mitchell, G Li, S Ding… - Journal of Biological …, 2003 - ASBMB
Infection with Helicobacter pylori, a Gram-negative, microaerophilic, flagellated bacteria that
adheres to human gastric mucosa, is strongly associated with gastric ulcers and …