Hearing loss is a severe high unmet need condition affecting more than 1.5 billion people
globally. There are no licensed medicines for the prevention, treatment or restoration of …

Abstract Grainyhead-like 2 (GRHL2), one of the three homologs of Drosophila grainyhead,
contributes to epithelial morphogenesis and differentiation. Dysregulation of GRHL2 has …

Among the transcription factors that are conserved across phylogeny, the grainyhead family
holds vital roles in driving the epithelial cell fate. In Drosophila, the function of grainyhead …

The metabotropic glutamate receptor 7 (mGluR7) is a presynaptic G-protein-coupled
glutamate receptor that modulates neurotransmitter release and synaptic plasticity at …

The prevalence of hearing loss-related diseases caused by different factors is increasing
worldwide year by year. Currently, however, the patient's hearing loss has not been …

Portions of this work were presented in “Medicines discovery for auditory disease: right drug,
right dose, right time, right patient,” Translational Hearing Research Summit: Biological and …

Age-related hearing loss (ARHL) or presbycusis shares common features with conditions
related to senescence and neurodegeneration. In this review, we explore the linking of …

Az öregedés által befolyásolt számos fiziológiás folyamat, illetve a retina különös
kiszolgáltatottsága ezekkel szemben több fontos és megválaszolandó kérdést felvet a retina …