Complement evasion by human pathogens
The human immune system has developed an elaborate network of cascades for dealing
with microbial intruders. Owing to its ability to rapidly recognize and eliminate …
with microbial intruders. Owing to its ability to rapidly recognize and eliminate …
[HTML][HTML] Complement evasion strategies of viruses: an overview
Being a major first line of immune defense, the complement system keeps a constant vigil
against viruses. Its ability to recognize large panoply of viruses and virus-infected cells, and …
against viruses. Its ability to recognize large panoply of viruses and virus-infected cells, and …
A double edged-sword-the complement system during SARS-CoV-2 infection
LE Santiesteban-Lores, TA Amamura, TF da Silva… - Life sciences, 2021 - Elsevier
In the past 20 years, infections caused by coronaviruses SARS-CoV, MERS-CoV and SARS-
CoV-2 have posed a threat to public health since they may cause severe acute respiratory …
CoV-2 have posed a threat to public health since they may cause severe acute respiratory …
[HTML][HTML] Microvesicles and intercellular communication in the context of parasitism
There is a rapidly growing body of evidence that production of microvesicles (MVs) is a
universal feature of cellular life. MVs can incorporate microRNA (miRNA), mRNA, mtDNA …
universal feature of cellular life. MVs can incorporate microRNA (miRNA), mRNA, mtDNA …
Structural principles within the human-virus protein-protein interaction network
EA Franzosa, Y Xia - … of the National Academy of Sciences, 2011 - National Acad Sciences
General properties of the antagonistic biomolecular interactions between viruses and their
hosts (exogenous interactions) remain poorly understood, and may differ significantly from …
hosts (exogenous interactions) remain poorly understood, and may differ significantly from …
Cross-talk between the complement pathway and the contact activation system of coagulation: activated factor XI neutralizes complement factor H
C Puy, J Pang, SE Reitsma, CU Lorentz… - The Journal of …, 2021 - journals.aai.org
Complement factor H (CFH) is the major inhibitor of the alternative pathway of the
complement system and is structurally related to beta2-glycoprotein I, which itself is known …
complement system and is structurally related to beta2-glycoprotein I, which itself is known …
[HTML][HTML] Predicted structural mimicry of spike receptor-binding motifs from highly pathogenic human coronaviruses
Viruses often encode proteins that mimic host proteins in order to facilitate infection. Little
work has been done to understand the potential mimicry of the SARS-CoV-2, SARS-CoV …
work has been done to understand the potential mimicry of the SARS-CoV-2, SARS-CoV …
Regulatory T cell-like responses in deer mice persistently infected with Sin Nombre virus
T Schountz, J Prescott, AC Cogswell… - Proceedings of the …, 2007 - National Acad Sciences
Hantavirus cardiopulmonary syndrome is a zoonotic illness associated with a systemic
inflammatory immune response, capillary leak, noncardiogenic pulmonary edema, and …
inflammatory immune response, capillary leak, noncardiogenic pulmonary edema, and …
Secreted immunomodulatory viral proteins as novel biotherapeutics
A Lucas, G McFadden - The Journal of immunology, 2004 - journals.aai.org
Many viruses have learned to evade or subvert the host antiviral immune responses by
encoding and expressing immunomodulatory proteins that protect the virus from attack by …
encoding and expressing immunomodulatory proteins that protect the virus from attack by …
Recent findings on the Coronavirus disease 2019 (COVID-19); immunopathogenesis and immunotherapeutics
Severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) is responsible for recent
ongoing public health emergency in the world. Sharing structural and behavioral similarities …
ongoing public health emergency in the world. Sharing structural and behavioral similarities …