Since the industrial revolution, the rapid growth and development of global industries have
depended largely upon the utilization of coal-derived chemicals, and more recently, the …

Flavoprotein monooxygenases (FPMOs) are single-or two-component enzymes that
catalyze a diverse set of chemo-, regio-and enantioselective oxyfunctionalization reactions …

The development of mild, efficient, and enantioselective methods for preparing chiral
fluorinated compounds has been a long‐standing challenge. Herein, we report a …

Pollution, accidents, and misinformation have earned the pharmaceutical and chemical
industry a poor public reputation, despite their undisputable importance to society …

This review covers the recent developments (since 2015) of enantioselective
desymmetrization reactions using metal-catalyzed, organocatalyzed and enzymatic …

Diaryl ketones are important building blocks for synthesizing pharmaceuticals and are
generally regarded as “difficult-to-reduce” ketones due to the large steric hindrance of their …

Abstract Baeyer-Villiger monooxygenases (BVMOs) are versatile biocatalysts for the
conversion of ketones to lactones or esters while also being able to efficiently oxidize …

Directed evolution is a powerful approach to engineer enzymes via iterative creation and
screening of variant libraries. However, assay development for high-throughput mutant …

Controlling the regioselectivity of Baeyer–Villiger (BV) reactions remains an ongoing issue
in organic chemistry, be it by synthetic catalysts or enzymes of the type Baeyer–Villiger …

Redox enzymes offer many powerful transformations for the efficient industrial-scale
synthesis of diverse chemicals desired by society. Here we survey recent preparative …