[HTML][HTML] Brain–gut–microbiota axis in depression: A historical overview and future directions
Depression is the most common mental disorder and a leading cause of disability
worldwide. Despite abundant research, the precise mechanisms underlying the …
worldwide. Despite abundant research, the precise mechanisms underlying the …
Detrimental effects of COVID-19 in the brain and therapeutic options for long COVID: the role of Epstein–Barr virus and the gut–brain axis
K Hashimoto - Molecular Psychiatry, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in a serious public …
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in a serious public …
Molecular mechanisms underlying the antidepressant actions of arketamine: beyond the NMDA receptor
The discovery of robust antidepressant actions exerted by the N-methyl-D-aspartate receptor
(NMDAR) antagonist (R, S)-ketamine has been a crucial breakthrough in mood disorder …
(NMDAR) antagonist (R, S)-ketamine has been a crucial breakthrough in mood disorder …
Emerging role of the host microbiome in neuropsychiatric disorders: overview and future directions
K Hashimoto - Molecular Psychiatry, 2023 - nature.com
The human body harbors a diverse ecosystem of microorganisms, including bacteria,
viruses, and fungi, collectively known as the microbiota. Current research is increasingly …
viruses, and fungi, collectively known as the microbiota. Current research is increasingly …
The gut microbiome and mental health: advances in research and emerging priorities
The gut microbiome exerts a considerable influence on human neurophysiology and mental
health. Interactions between intestinal microbiology and host regulatory systems have now …
health. Interactions between intestinal microbiology and host regulatory systems have now …
Toward a deeper understanding of gut microbiome in depression: the promise of clinical applicability
L Liu, H Wang, H Zhang, X Chen, Y Zhang… - Advanced …, 2022 - Wiley Online Library
The emergence of the coronavirus disease 2019 pandemic has dramatically increased the
global prevalence of depression. Unfortunately, antidepressant drugs benefit only a small …
global prevalence of depression. Unfortunately, antidepressant drugs benefit only a small …
[HTML][HTML] Brain-spleen axis in health and diseases: A review and future perspective
The spleen, an important tissue for the immune system, acts as a filter for blood within the
immune system. Accumulating evidence suggests that the spleen affects a number of brain …
immune system. Accumulating evidence suggests that the spleen affects a number of brain …
A role of the subdiaphragmatic vagus nerve in depression-like phenotypes in mice after fecal microbiota transplantation from Chrna7 knock-out mice with depression …
The α7 subtype of the nicotinic acetylcholine receptor (α7 nAChR: coded by Chrna7)
regulates the cholinergic ascending anti-inflammatory pathway involved in depression. We …
regulates the cholinergic ascending anti-inflammatory pathway involved in depression. We …
Antibiotics and mental health: The good, the bad and the ugly
K Dinan, T Dinan - Journal of Internal Medicine, 2022 - Wiley Online Library
Antibiotics are recognised as, on occasion, producing psychiatric side effects, most notably
depression and anxiety. Apart from antimicrobial activity, antibiotics have multiple off‐target …
depression and anxiety. Apart from antimicrobial activity, antibiotics have multiple off‐target …
Gut microbiota in anxiety and depression: unveiling the relationships and management options
The gut microbiota is critical for maintaining human health and the immunological system.
Several neuroscientific studies have shown the significance of microbiota in developing …
Several neuroscientific studies have shown the significance of microbiota in developing …