Molecular basis of androgenetic alopecia: From androgen to paracrine mediators through dermal papilla

S Inui, S Itami - Journal of dermatological science, 2011 - Elsevier
Androgenetic alopecia (AGA) is characterized by vellus transformation of scalp hairs,
corresponding to hair follicle miniaturization during repeated hair cycles with shortened …

An updated etiology of hair loss and the new cosmeceutical paradigm in therapy: Clearing 'the big eight strikes'

N Sadgrove, S Batra, D Barreto, J Rapaport - Cosmetics, 2023 - mdpi.com
In this current review, research spanning the last decade (such as transcriptomic studies,
phenotypic observations, and confirmed comorbidities) has been synthesized into an …

Hair growth promoting activity of Eclipta alba in male albino rats

RK Roy, M Thakur, VK Dixit - Archives of dermatological research, 2008 - Springer
Alopecia is a dermatological disorder with psychosocial implications on patients with hair
loss. Eclipta alba Hassk. is a well-known Ayurvedic herb with purported claims of hair growth …

The effect of plasma rich in growth factors on pattern hair loss: a pilot study

E Anitua, A Pino, N Martinez, G Orive… - Dermatologic …, 2017 - journals.lww.com
BACKGROUND Autologous growth factors have proved to promote tissue regeneration in
various medical fields. Recent findings suggest that platelet rich plasma may also play an …

Effectiveness of dutasteride in a large series of patients with frontal fibrosing alopecia in real clinical practice

C Pindado-Ortega, D Saceda-Corralo… - Journal of the American …, 2021 - Elsevier
Background Dutasteride has been proposed as an effective therapy for frontal fibrosing
alopecia (FFA). Objectives We sought to describe the therapeutic response to dutasteride …

Formulation Development and Investigations on Therapeutic Potential of Nanogel from Beta vulgaris L. Extract in Testosterone‐Induced Alopecia

S Singh, Sonia, RK Sindhu… - BioMed Research …, 2023 - Wiley Online Library
The objective of the present study was to develop a novel nanogel containing Beta vulgaris
L. hydroalcoholic extract and assess its efficacy for treating testosterone‐induced alopecia …

[HTML][HTML] A hypothetical pathogenesis model for androgenic alopecia: clarifying the dihydrotestosterone paradox and rate-limiting recovery factors

RS English Jr - Medical Hypotheses, 2018 - Elsevier
Androgenic alopecia, also known as pattern hair loss, is a chronic progressive condition that
affects 80% of men and 50% of women throughout a lifetime. But despite its prevalence and …

[HTML][HTML] Frontal fibrosing alopecia: An update on the hypothesis of pathogenesis and treatment

S Tavakolpour, HR Mahmoudi, R Abedini… - International Journal of …, 2019 - Elsevier
Frontal fibrosing alopecia (FFA) is a relatively new scarring alopecia that is considered a
variant of lichen planopilaris (LPP) with no recognized promising treatments. In this study …

[PDF][PDF] New insight into the pathophysiology of hair loss trigger a paradigm shift in the treatment approach

NS Sadick, VD Callender, LH Kircik, S Kogan - J Drugs Dermatol, 2017 - im-athletic.com
Androgens, genetic susceptibility, chronic inflammation, oxidative stress, internal and
external environmental triggers such as ultraviolet light, pollutants, aging, poor nutrition, as …

[HTML][HTML] Induction of transforming growth factor-beta 1 by androgen is mediated by reactive oxygen species in hair follicle dermal papilla cells

H Shin, HG Yoo, S Inui, S Itami, IG Kim, AR Cho… - BMB …, 2013 - ncbi.nlm.nih.gov
The progression of androgenetic alopecia is closely related to androgen-inducible
transforming growth factor (TGF)-β1 secretion by hair follicle dermal papilla cells (DPCs) in …