Activated neutrophils release neutrophil extracellular traps (NETs) in response to a variety of
stimuli. NETosis is driven by protein-arginine deiminase type 4, with the release of …

In addition to physical barriers, neutrophils are considered a part of the first line of immune
defense. They can be found in the bloodstream, with a lifespan of 6–8 h, and in tissue …

Spectacular images of neutrophils ejecting nuclear chromatin and bactericidal proteins, in
response to microbes, were first reported in 2004. As externalized chromatin could entangle …

Neutrophil extracellular traps (NETs) are chromatin structures loaded with antimicrobial
molecules. They can trap and kill various bacterial, fungal and protozoal pathogens, and …

Neutrophils (PMNs) and cytokines have a critical role to play in host defense and systemic
inflammatory response syndrome (SIRS). Neutrophil extracellular traps (NETs) have been …

As key players in the host innate immune response, neutrophils are recruited to sites of
infection and constitute the first line of defense. They employ three strategies to eliminate …

Neutrophils are the foot soldiers of the immune system. They home in to the site of infection
and kill pathogens by phagocytosis, degranulation, and the release of web-like structures …

Neutrophils are short-lived leukocytes that die by apoptosis, necrosis, and NETosis. Upon
death by NETosis, neutrophils release fibrous traps of DNA, histones, and granule proteins …

Under normal conditions, neutrophils are restricted from trafficking into the brain
parenchyma and cerebrospinal fluid by the presence of the brain–blood barrier (BBB). Yet …

Neutrophils are produced in the bone marrow and then patrol blood vessels from which they
can be rapidly recruited to a site of infection. Neutrophils bind, engulf, and efficiently kill …