Compositions and methods for modifying genomes

M Begemann, BN Gray - US Patent 9,896,696, 2018 - Google Patents
Compositions and methods for modifying genomic DNA sequences are provided. The
methods produce double-stranded breaks (DSBs) at pre-determined target sites in a …

Nucleic acid-guided nucleases

RT Gill, A Garst, TEW Lipscomb - US Patent 9,982,279, 2018 - Google Patents
2017-08-22 Assigned to MUSE BIOTECHNOLOGY, INC. reassignment MUSE
BIOTECHNOLOGY, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …

Interfacing with a vehicular controller area network

C King, B Bhattacharyya, S Friedman - US Patent 10,650,621, 2020 - Google Patents
A vehicle monitoring system, comprising: an interface configured to at least communicate
with a controller area network bus; a remote data telecommunication interface; a database; …

Automated cell processing methods, modules, instruments, and systems

D Masquelier, P Belgrader, J Bernate, R Gill… - US Patent …, 2019 - Google Patents
US10329559B1 - Automated cell processing methods, modules, instruments, and systems -
Google Patents US10329559B1 - Automated cell processing methods, modules …

Methods for generating barcoded combinatorial libraries

RT Gill, A Garst, TEW Lipscomb, MC Bassalo… - US Patent …, 2019 - Google Patents
2018-05-22 Assigned to THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY
CORPORATE reassignment THE REGENTS OF THE UNIVERSITY OF COLORADO, A …

Fusions of Cas9 domains and nucleic acid-editing domains

DR Liu, AC Komor - US Patent 11,053,481, 2021 - Google Patents
Some aspects of this disclosure provide strategies, systems, reagents, methods, and kits that
are useful for the targeted editing of nucleic acids, including editing a single site within the …

Nucleic acid-guided nucleases

RT Gill, A Garst, TEW Lipscomb - US Patent 10,011,849, 2018 - Google Patents
2017-08-22 Assigned to MUSE BIOTECHNOLOGY, INC. reassignment MUSE
BIOTECHNOLOGY, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …

Using programmable DNA binding proteins to enhance targeted genome modification

F Chen - US Patent 10,266,851, 2019 - Google Patents
2014/0273233 A1 9/2014 Chen et al. 2014/0315985 Al 10/2014 May et al. 2015/0044772 Al
2/2015 Zhao 2016/0002670 A1 1/2016 Church et al. 2016/0017366 Al 1/2016 Chen et al …

Use of cationic lipids to deliver CAS9

DR Liu, JA Zuris, DB Thompson - US Patent 9,737,604, 2017 - Google Patents
2014-11-04 Assigned to PRESIDENT AND FELLOWS OF HARVARD COLLEGE
reassignment PRESIDENT AND FELLOWS OF HARVARD COLLEGE ASSIGNMENT OF …

Delivery system for functional nucleases

DR Liu, JA Zuris, DB Thompson - US Patent 9,526,784, 2016 - Google Patents
2014-11-04 Assigned to PRESIDENT AND FELLOWS OF HARVARD COLLEGE
reassignment PRESIDENT AND FELLOWS OF HARVARD COLLEGE ASSIGNMENT OF …