B cell abnormalities in systemic lupus erythematosus and lupus nephritis—role in pathogenesis and effect of immunosuppressive treatments
Abnormalities in B cells play pivotal roles in the pathogenesis of systemic lupus
erythematosus (SLE) and lupus nephritis (LN). Breach in central and peripheral tolerance …
erythematosus (SLE) and lupus nephritis (LN). Breach in central and peripheral tolerance …
KDIGO 2021 clinical practice guideline for the management of glomerular diseases
BH Rovin, SG Adler, J Barratt, F Bridoux… - Kidney …, 2021 - kidney-international.org
Glomerular disease, be it primary or secondary, occurring in the setting of systemic
autoimmune diseases, infections, drugs, or malignancy, affects individuals of all ages. In …
autoimmune diseases, infections, drugs, or malignancy, affects individuals of all ages. In …
2019 update of the joint European League Against Rheumatism and European Renal Association–European Dialysis and Transplant Association (EULAR/ERA …
A Fanouriakis, M Kostopoulou, K Cheema… - Annals of the …, 2020 - ard.bmj.com
Objective To update the 2012 EULAR/ERA–EDTA recommendations for the management of
lupus nephritis (LN). Methods Following the EULAR standardised operating procedures, a …
lupus nephritis (LN). Methods Following the EULAR standardised operating procedures, a …
Flares in lupus nephritis: risk factors and strategies for their prevention
A Banos, G Bertsias - Current Rheumatology Reports, 2023 - Springer
Abstract Purpose of Review Discuss the prognostic significance of kidney flares in patients
with lupus nephritis, associated risk factors, and possible preventative strategies. Recent …
with lupus nephritis, associated risk factors, and possible preventative strategies. Recent …
Changing patterns in clinical–histological presentation and renal outcome over the last five decades in a cohort of 499 patients with lupus nephritis
G Moroni, PG Vercelloni, S Quaglini, M Gatto… - Annals of the …, 2018 - ard.bmj.com
Objectives To evaluate changes in demographic, clinical and histological presentation, and
prognosis of lupus nephritis (LN) over time. Patients and methods We studied a multicentre …
prognosis of lupus nephritis (LN) over time. Patients and methods We studied a multicentre …
KDIGO 2024 Clinical Practice Guideline for the management of LUPUS NEPHRITIS
BH Rovin, IM Ayoub, TM Chan, ZH Liu… - Kidney …, 2024 - kidney-international.org
This article is published as part of a supplement sponsored by Kidney Disease: Improving
Global Outcomes (KDIGO). The opinions or views expressed in this supplement are those of …
Global Outcomes (KDIGO). The opinions or views expressed in this supplement are those of …
[HTML][HTML] Kidney biopsy–based management of maintenance immunosuppression is safe and may ameliorate flare rate in lupus nephritis
A Malvar, V Alberton, B Lococo, M Ferrari, P Delgado… - Kidney international, 2020 - Elsevier
The optimal duration of maintenance immunosuppressive therapy for patients with lupus
nephritis who have achieved clinical remission has not been established. Furthermore …
nephritis who have achieved clinical remission has not been established. Furthermore …
Long-term outcomes with rituximab as add-on therapy in severe childhood-onset lupus nephritis
EY Chan, S Wong, FF Lai, T Ho, P Tong, W Lai… - Pediatric …, 2023 - Springer
Background Long-term data pertaining to rituximab as add-on therapy in childhood-onset
lupus nephritis (cLN) is scarce. Methods A retrospective cohort study was conducted on all …
lupus nephritis (cLN) is scarce. Methods A retrospective cohort study was conducted on all …
Belimumab and antimalarials combined against renal flares in patients treated for extra-renal systemic lupus erythematosus: results from 4 phase III clinical trials
Objectives To determine the effect of antimalarial agents (AMA) and different doses and
pharmaceutical forms of belimumab on preventing renal flares in patients with SLE treated …
pharmaceutical forms of belimumab on preventing renal flares in patients with SLE treated …
Machine learning for prediction and risk stratification of lupus nephritis renal flare
Y Chen, S Huang, T Chen, D Liang, J Yang… - American Journal of …, 2021 - karger.com
Background: Renal flare of lupus nephritis (LN) is strongly associated with poor kidney
outcomes, and predicting renal flare and stratifying its risk are important for clinical decision …
outcomes, and predicting renal flare and stratifying its risk are important for clinical decision …