The molecular mechanism of vitamin E as a bone-protecting agent: a review on current evidence
Bone remodelling is a tightly-coordinated and lifelong process of replacing old damaged
bone with newly-synthesized healthy bone. In the bone remodelling cycle, bone resorption …
bone with newly-synthesized healthy bone. In the bone remodelling cycle, bone resorption …
Natural food dyes on dairy products: A critical approach between 2012-2023 literature regarding the technological and functional aspects, health benefits and future …
MEM Soutelino, G de Paiva Vieira, MB Goulart… - Trends in Food Science …, 2024 - Elsevier
Background Synthetic dyes consumption, such as tartrazine, quinoline yellow, sunset
yellow, azorubine, ponceau 4 R, erythrosine, allura red, patent blue, indigo carmine, brilliant …
yellow, azorubine, ponceau 4 R, erythrosine, allura red, patent blue, indigo carmine, brilliant …
[HTML][HTML] Therapeutic potential of annatto tocotrienol with self-emulsifying drug delivery system in a rat model of postmenopausal bone loss
Tocotrienol has been shown to prevent bone loss in animal models of postmenopausal
osteoporosis, but the low oral bioavailability might limit its use. A self-emulsifying drug …
osteoporosis, but the low oral bioavailability might limit its use. A self-emulsifying drug …
[HTML][HTML] Effects of emulsified and non-emulsified palm tocotrienol on bone and joint health in ovariectomised rats with monosodium iodoacetate-induced osteoarthritis
SO Ekeuku, MLN Muhamad, AA Aminuddin… - Biomedicine & …, 2024 - Elsevier
Postmenopausal women are susceptible to osteoporosis and osteoarthritis. Tocotrienol, a
bone-protective nutraceutical, is reported to prevent osteoarthritis in male rats. However, its …
bone-protective nutraceutical, is reported to prevent osteoarthritis in male rats. However, its …
Tocotrienol as a protecting agent against glucocorticoid-induced osteoporosis: a mini review of potential mechanisms
SO Ekeuku, ES Mohd Ramli, N Abdullah Sani… - Molecules, 2022 - mdpi.com
Glucocorticoid-induced osteogenic dysfunction is the main pathologyical mechanism
underlying the development of glucocorticoid-induced osteoporosis. Glucocorticoids …
underlying the development of glucocorticoid-induced osteoporosis. Glucocorticoids …
[HTML][HTML] Self-emulsified annatto tocotrienol improves bone histomorphometric parameters in a rat model of oestrogen deficiency through suppression of skeletal …
NV Mohamad, S Ima-Nirwana… - International Journal of …, 2021 - ncbi.nlm.nih.gov
Menopause is the leading cause of osteoporosis for elderly women due to imbalanced bone
remodelling in the absence of oestrogen. The ability of tocotrienol in reversing established …
remodelling in the absence of oestrogen. The ability of tocotrienol in reversing established …
Beneficial effects of δ-tocotrienol against oxidative stress in osteoblastic cells: Studies on the mechanisms of action
L Casati, F Pagani, P Limonta, C Vanetti… - European journal of …, 2020 - Springer
Purpose Natural antioxidants are considered as promising compounds in the
prevention/treatment of osteoporosis. We studied the ability of purified δ-tocotrienol (δ-TT) …
prevention/treatment of osteoporosis. We studied the ability of purified δ-tocotrienol (δ-TT) …
Annatto-derived tocotrienol stimulates osteogenic activity in preosteoblastic MC3T3-E1 cells: A temporal sequential study
WN Wan Hasan, N Abd Ghafar, KY Chin… - Drug design …, 2018 - Taylor & Francis
Purpose Annatto-derived tocotrienol (AnTT) has been shown to improve bone formation in
animal models of osteoporosis. However, detailed studies of the effects of AnTT on …
animal models of osteoporosis. However, detailed studies of the effects of AnTT on …
The role of tocotrienol in preventing male osteoporosis—A review of current evidence
KY Chin, S Ima-Nirwana - International journal of molecular sciences, 2019 - mdpi.com
Male osteoporosis is a significant but undetermined healthcare problem. Men suffer from a
higher mortality rate post-fracture than women and they are marginalized in osteoporosis …
higher mortality rate post-fracture than women and they are marginalized in osteoporosis …
Food for bone: evidence for a role for delta-tocotrienol in the physiological control of osteoblast migration
Bone remodeling and repair require osteogenic cells to reach the sites that need to be
rebuilt, indicating that stimulation of osteoblast migration could be a promising …
rebuilt, indicating that stimulation of osteoblast migration could be a promising …